C2ORF25 (MMADHC) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1G4]
$509.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1G4 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 39-296 of human MMADHC (NP_056517) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Biotin |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 32.8 kDa |
| Gene Name | methylmalonic aciduria and homocystinuria, cblD type |
| Database Link | |
| Background | This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X. [provided by RefSeq, Nov |
| Synonyms | C2orf25; cblD; CL25022 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
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Resources
Other "OTI1G4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF800573 | Carrier-free (BSA/glycerol-free) MMADHC mouse monoclonal antibody, clone OTI1G4 (formerly 1G4) | 100 ug |
$620.00
|
|
| TA800573 | MMADHC mouse monoclonal antibody, clone OTI1G4 (formerly 1G4) | 100 ul |
$447.00
|
|
| TA800573BM | MMADHC mouse monoclonal antibody,clone 1G4, HRP conjugated | 100 ul |
$509.00
|
|
| TA800573S | MMADHC mouse monoclonal antibody, clone OTI1G4 (formerly 1G4) | 30 ul |
$200.00
|
|
Citations
Mitochondrial depolarization stabilizes the vitamin B12 chaperone MMADHC in the cytosol to increase MTR activity
Rath, Li, Guha et al
Proc Natl Acad Sci U S A (2026) 123 (37), e2537797123 DOI: 10.1073/pnas.2537797123
Rath, Li, Guha et al
Proc Natl Acad Sci U S A (2026) 123 (37), e2537797123 DOI: 10.1073/pnas.2537797123
Cited by 1
AI Summary: OriGene’s Mouse monoclonal anti-MMADHC antibody (Cat# TA800573) was used in this study to detect and analyze MMADHC protein levels, helping to demonstrate how mitochondrial depolarization stabilizes MMADHC in the cytosol and increases MTR activity.
Snippet: Mouse monoclonal anti-MMADHC Origene Cat#TA800573;RRID:AB_2625545 Rabbit polyclonal anti-MMADHC Abcam Cat#ab204313 RRID:AB_3696890 Rabbit monoclonal anti-PINK1 Abcam Cat#ab216144 RRID: AB_2927726
Showing 1-1 of 1 papers.
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