BNP (NPPB) Rabbit Monoclonal Capture Antibody [Clone ID: OTIR5G8]
Specifications
| Product Data | |
| Clone Name | OTIR5G8 |
|---|---|
| Application | ELISA, LMNX |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human BNP. The exact sequence is proprietary. |
| Buffer | PBS (pH 7.3) containing 0.05% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. Avoid repeat freeze/thaw cycles. |
| Shipping | Blue Ice |
| Predicted Protein Size | 14.7 kDa |
| Gene Name | natriuretic peptide B |
| Database Link | |
| Background | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. provided by RefSeq, Aug 2020 |
| Synonyms | BNP; Iso-ANP |
| Matched ELISA Pair | TA700562 |
| Reference Data | |
| Protein Categories | Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein, Stem cell - Pluripotency |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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