S100 beta (S100B) Mouse Monoclonal Capture Antibody [Clone ID: OTI6A6]

SKU TA600560

S100B Capture Mouse Monoclonal antibody, clone OTI6A6

Product Data

• Clone Name: OTI6A6
• Application: ELISA, LMNX
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human S100B (NP_006263) produced in HEK293T cell.
• Buffer: PBS (pH7.3) containing 0.05% sodium azide
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C.; Avoid repeat freeze/thaw cycles.
• Shipping: Blue Ice
• Predicted Protein Size: 10.7 kDa
• Gene Name: S100 calcium binding protein B
• Database Link:
  NP_006263
  P04271
• Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
• Synonyms: NEF; S100; S100-B; S100beta
• Matched ELISA Pair: TA700560

Reference Data