IL17 (IL17A) Mouse Monoclonal Capture Antibody [Clone ID: OTI1G8]
Specifications
| Product Data | |
| Clone Name | OTI1G8 |
|---|---|
| Application | ELISA, LMNX |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human IL-17A (NP_002181) produced in 293 cell. |
| Buffer | PBS (pH 7.3) containing 0.05% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. Avoid repeat freeze/thaw cycles. |
| Shipping | Blue Ice |
| Predicted Protein Size | 17.5 kDa |
| Gene Name | interleukin 17A |
| Database Link | |
| Background | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. provided by RefSeq, Jul 2008 |
| Synonyms | CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17 |
| Matched ELISA Pair | TA600555, TA700556 |
| Reference Data | |
| Protein Categories | Chemokines, Cytokines, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction |
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