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SOD2 Rabbit Monoclonal Antibody [Clone ID: OTIR4G8]

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SKU
TA591033
Rabbit monoclonal anti-SODM antibody for SISCAPA, clone OTIR4G8
Size:
100 ul
Conjugation:
Unconjugated
  $519.00
In Stock*
Bulk/Customize

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View other "SOD2 or NM_000636" antibodies

Specifications
Specifications
Product Data
Clone Name OTIR4G8
Application SISCAPA
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SOD2 (NP_000627). The exact sequence is proprietary.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration Lot dependent; please refer to CoA along with shipment
Purification Purified from cell culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 24.8 kDa
Gene Name superoxide dismutase 2
Database Link
Background This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. provided by RefSeq, Apr 2016
Synonyms GClnc1; IPO-B; IPOB; Mn-SOD; MNSOD; MVCD6
Reference Data
Protein Categories Endocrine and metabolic diseases, Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Huntington's disease
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Documents
Resources

file-alt Citations

Sirtuin 3 Ameliorates Lung Senescence and Improves Type II Alveolar Epithelial Cell Function by Enhancing the FoxO3a-Dependent Antioxidant Defense Mechanism
Chen, Yang, Sun et al
Stem Cells Dev (2021)
Cited by 27
AI Summary: In this study, OriGene’s rabbit anti-SOD2 monoclonal antibody was used to assess the expression of manganese superoxide dismutase (MnSOD), contributing to the evaluation of antioxidant defense mechanisms in type II alveolar epithelial cells.
Snippet: anti-SIRT3 monoclonal antibody (Cell Signaling Technology, Danvers, MA, USA), rabbit anti- SOD2 monoclonal antibody (MnSOD;OriGene, Beijing, China), rabbit anti-CAT monoclonal (Abcam, Cambridge, UK), rabbit anti-FoxO3a monoclonal antibody (Abcam), rabbit
SIRT3 Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair
Zhang, Gao, Xu et al
Rejuvenation Res (2020)
Cited by 27
AI Summary: OriGene's anti-SOD2 (MnSOD) antibody was used in this study to detect MnSOD protein levels, helping to assess the antioxidant effects of SIRT3 transfection in aged human bone marrow-derived mesenchymal stem cells.
Snippet: …antibody against SOD2 (1:1000, MnSOD, OriGene, Beijing, China), rabbit monoclonal antibody against FOXO3a (1:2500, Abcam), rabbit polyclonal antibody against;- ndergo cop ye diting an d proof corre ction. … antibody against SOD2 (1:1000, MnSOD, OriGene, Beijing, China), rabbit monoclonal antibody against FOXO3a (1:2500, Abcam), rabbit polyclonal antibody against
Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress
Wang, Shao, Ma et al
J. Cell. Mol. Med. (2014)
Cited by 56
AI Summary: OriGene’s rabbit monoclonal antibody against SOD2 (MnSOD) was used in this study to assess antioxidant enzyme levels, helping demonstrate how changes in SIRT3 affect cellular resistance to oxidative stress in human mesenchymal stromal/stem cells.
Snippet: Antibodies used were as follows: SirT3 (C73E3) rabbit mAb (Cell Signaling Technology, Danvers, Massachusetts, USA), rabbit monoclonal antibody against SOD2 (MnSOD, OriGene, Beijing, China), mouse anti-β-actin monoclonal antibody (ZSGB-BIO), fluorescein- ... Cite SaveSaving
Showing 1-3 of 3 papers.
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