XRCC3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA |
|---|---|
| Recommended Dilution | WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | DNA immunization. This antibody is specific for the C Terminus Region of the target protein. |
| Buffer | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
| Concentration | 1.04mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | X-ray repair cross complementing 3 |
| Database Link | |
| Background | Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homolgs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes.XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination. |
| Synonyms | CMM6 |
| Note | This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT |
| Reference Data | |
| Protein Categories | Cancer: Gynecologic, Cancer: Skin, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Homologous recombination |
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