DR5 (TNFRSF10B) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA |
|---|---|
| Recommended Dilution | WB: 1:5000-1:20000; ELISA: 1:100-1:2000; FC 1:10-1:1000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | DNA immunization. This antibody is specific for the N Terminus Region of the target protein. |
| Buffer | 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0 |
| Concentration | 0.99mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | TNF receptor superfamily member 10b |
| Database Link | |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracelluar death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. |
| Synonyms | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 |
| Note | This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT |
| Reference Data | |
| Protein Categories | Cancer: Head and Neck, CD Markers, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
