Munc 13 4 (UNC13D) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1F4]

SKU TA507267AM

UNC13D mouse monoclonal antibody, clone OTI1F4 (formerly 1F4), Biotinylated

Product Data

• Clone Name: OTI1F4
• Application: WB
• Recommended Dilution: WB 1:200~1000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human UNC13D(NP_954712) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 123.1 kDa
• Gene Name: unc-13 homolog D
• Database Link:
  NP_954712
  Q70J99
• Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
• Synonyms: FHL3; HLH3; HPLH3; Munc13-4

Reference Data