PMS2 Mouse Monoclonal Antibody [Clone ID: OTI2G5]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2G5 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:150, IF: 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 95.6 kDa |
| Gene Name | PMS1 homolog 2, mismatch repair system component |
| Database Link | |
| Background | This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. provided by RefSeq, Jul 2008 |
| Synonyms | HNPCC4; PMS2CL; PMSL2 |
| Reference Data | |
| Protein Categories | ADC Targets, Cancer: Gastrointestinal, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Mismatch repair |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI2G5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF506658 | Carrier-free (BSA/glycerol-free) PMS2 mouse monoclonal antibody, clone OTI2G5 (formerly 2G5) | 100 ug |
$620.00
|
|
| TA506658AM | PMS2 mouse monoclonal antibody,clone 2G5, Biotinylated | 100 ul |
$509.00
|
|
| TA506658BM | PMS2 mouse monoclonal antibody,clone 2G5, HRP conjugated | 100 ul |
$509.00
|
|
| TA506658S | PMS2 mouse monoclonal antibody, clone OTI2G5 (formerly 2G5) | 30 ul |
$200.00
|
|
Citations
Pathological prognostic factors of pseudomyxoma peritonei: comprehensive clinicopathological analysis of 155 cases
Yan, Lin, Zhou et al
Hum. Pathol. (2020) 97, 9-18 DOI: 10.1016/j.humpath.2019.12.008
Yan, Lin, Zhou et al
Hum. Pathol. (2020) 97, 9-18 DOI: 10.1016/j.humpath.2019.12.008
Cited by 26
AI Summary: OriGene products contributed to this study by providing primary antibodies for immunohistochemical analysis, specifically MUC1 (clone MRQ-17), MUC2 (clone MRQ-18), MUC5AC (clone MRQ-19), MUC6 (clone MRQ-20), and MLH1 (clone ES05), which were used to evaluate pathological markers in pseudomyxoma peritonei specimens.
Showing 1-1 of 1 papers.
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