Tyrosine Hydroxylase (TH) Mouse Monoclonal Antibody [Clone ID: OTI3G3]
Specifications
| Product Data | |
| Clone Name | OTI3G3 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:4000, IF 1:100, IHC: 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human TH(NP_000351) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | tyrosine hydroxylase |
| Database Link | |
| Background | The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. provided by RefSeq, Jul 2008 |
| Synonyms | DYT5b; DYT14; TYH |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Parkinson's disease, Tyrosine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3G3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF506549 | Carrier-free (BSA/glycerol-free) TH mouse monoclonal antibody, clone OTI3G3 (formerly 3G3) | 100 ug |
$620.00
|
|
| TA506549AM | TH mouse monoclonal antibody,clone 3G3, Biotinylated | 100 ul |
$509.00
|
|
| TA506549BM | TH mouse monoclonal antibody,clone 3G3, HRP conjugated | 100 ul |
$509.00
|
|
| TA506549S | TH mouse monoclonal antibody, clone OTI3G3 (formerly 3G3) | 30 ul |
$200.00
|
|
Citations
Pavan, Davidson, Payne et al
Cell Stem Cell (2025) 32 (5), 710-726.e8 DOI: 10.1016/j.stem.2025.03.008
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