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PDGF Receptor beta (PDGFRB) Mouse Monoclonal Antibody [Clone ID: OTI1E8]

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SKU
TA506230S
PDGFRB mouse monoclonal antibody, clone OTI1E8 (formerly 1E8)
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $200.00
In Stock*
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View other "PDGF Receptor beta or NM_002609" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1E8
Application IF, IHC, WB
Recommended Dilution WB 1:4000, IHC 1:150, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDGFRB(NP_002600) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name platelet derived growth factor receptor beta
Database Link
Background This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. provided by RefSeq, Jul 2008
Synonyms CD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1
Reference Data
Protein Categories Cancer: Brain and CNS, CD Markers, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
Protein Pathways Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
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Other "OTI1E8" antibodies (4)
SKU Description Size Price
CF506230 Carrier-free (BSA/glycerol-free) PDGFRB mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 100 ug
$620.00
TA506230 PDGFRB mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 100 ul
$447.00
TA506230AM PDGFRB mouse monoclonal antibody,clone 1E8, Biotinylated 100 ul
$509.00
TA506230BM PDGFRB mouse monoclonal antibody,clone 1E8, HRP conjugated 100 ul
$509.00

file-alt Citations

Identification of PDGFRB as a prognostic immune-related biomarker in gastric cancer through bioinformatics and clinical analysis
Wang, Meng, Liu et al
Transl Cancer Res (2025) 14 (10), 6849-6863 DOI: 10.21037/tcr-2025-859
Cited by 2
AI Summary: OriGene’s PDGFRB primary antibody (Cat: TA506230, clone ID: OTI1E8) was used for immunohistochemical analysis to assess PDGFRB protein expression in gastric cancer tissue samples, contributing to the identification of PDGFRB as a prognostic biomarker in the study.
Snippet: … After cooling to room temperature, the sections were immersed in peroxidase inhibitor for 10 minutes to block endogenous peroxidase activity. Subsequently, the sections were incubated overnight at 4 ℃ with the primary antibody PDGFRB (1:250, Cat: TA506230, clone ID: OTI1E8, Origene Technologies, USA). …
FigureFigureFigure
Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
Mayr, Simon, Leuschner et al
EMBO Mol Med (2021)
Cited by 109
AI Summary: OriGene’s mouse anti-PDGFRβ antibody (TA506230) was used for immunostaining to identify and analyze specific cell populations in lung tissue, contributing to the study’s investigation of cell state changes in lung fibrosis.
Snippet: rat anti‐KRT8 (University of Iowa Hybridoma Bank, 1:200), mouse anti‐PDGFRβ (Origene, TA506230, 1:50),
Showing 1-2 of 2 papers.
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