GLB1 Mouse Monoclonal Antibody [Clone ID: OTI10B2]

CAT#: TA505625

GLB1 mouse monoclonal antibody, clone OTI10B2 (formerly 10B2)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GLB1 (RC200721, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GLB1.

• 

  Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-GLB1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

• 

  Immunofluorescent staining of HeLa cells using anti-GLB1 mouse monoclonal antibody (TA505625).

Specifications

Product Data

• Clone Name: OTI10B2
• Applications: IF, WB
• Recommended Dilution: WB 1:200~2000, IF 1:100
• Reactivities: Human, Dog, Rat, Monkey, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GLB1(NP_001073279) produced in HEK293T cell.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 72.6 kDa
• Gene Name: galactosidase beta 1
• Database Link:
  NP_001073279
  Entrez Gene 12091 MouseEntrez Gene 316033 RatEntrez Gene 403873 DogEntrez Gene 709355 MonkeyEntrez Gene 2720 Human
  UniProt ID P16278
• Background: This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
• Synonyms: EBP; ELNR1; MPS4B

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Galactose metabolism, Glycosaminoglycan degradation, Glycosphingolipid biosynthesis - ganglio series, Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism