PCDH7 Mouse Monoclonal Antibody [Clone ID: OTI2G6]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2G6 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | WB 1:200~2000, IF 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PCDH7(NP_115833) produced in HKE293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 132.4 kDa |
| Gene Name | protocadherin 7 |
| Database Link | |
| Background | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. provided by RefSeq, Jul 2008 |
| Synonyms | BH-Pcdh; BHPCDH; PPP1R120 |
| Note | WB application: Only overexpression results are guaranteed, not endogenous |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI2G6" antibodies (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505452 | Carrier-free (BSA/glycerol-free) PCDH7 mouse monoclonal antibody, clone OTI2G6 (formerly 2G6) | 100 ug |
$620.00
|
|
| TA505452AM | PCDH7 mouse monoclonal antibody,clone 2G6, Biotinylated | 100 ul |
$509.00
|
|
| TA505452BM | PCDH7 mouse monoclonal antibody,clone 2G6, HRP conjugated | 100 ul |
$509.00
|
|
| TA505452S | PCDH7 mouse monoclonal antibody, clone OTI2G6 (formerly 2G6) | 30 ul |
$200.00
|
|
| TA700265 | PCDH7 biotinylated mouse monoclonal detection antibody, validated for Luminex assays | 50 ug |
$494.00
|
|
Citations
PP2A-Mediated GSK3β Dephosphorylation Is Required for Protocadherin-7-Dependent Regulation of Small GTPase RhoA in Osteoclasts
Kim, Takegahara, Choi
Cells (2023) 12 (15) DOI: 10.3390/cells12151967
Kim, Takegahara, Choi
Cells (2023) 12 (15) DOI: 10.3390/cells12151967
Cited by 7
AI Summary: In this study, OriGene’s mouse Pcdh7 shRNA (TL502431) and mouse Pcdh7 cDNA (MR209316) were used to manipulate Pcdh7 expression levels, enabling the authors to investigate the role of Pcdh7 in regulating PP2A-mediated GSK3β dephosphorylation and RhoA activation during osteoclast differentiation.
PP2A-Mediated GSK3β Dephosphorylation Is Required for Protocadherin-7-Dependent Regulation of Small GTPase RhoA in Osteoclasts
Kim, Takegahara, Choi
Cells (2023) 12 (15), 1967 DOI: 10.3390/cells12151967
Kim, Takegahara, Choi
Cells (2023) 12 (15), 1967 DOI: 10.3390/cells12151967
Cited by 7
AI Summary: OriGene’s anti-Pcdh7 antibody (Cat.# TA505452) was used in this study to detect Pcdh7 protein expression by western blotting, enabling the investigation of its role in osteoclast differentiation and signaling pathways.
Snippet: ern blotting was performed with the following antibodies: anti-PP2A−A, anti-PP2A−B, and anti-PP2A−C [Cat.# 9780T, Cell Signaling Technology (CST), Beverly, MA, USA], anti-Pcdh7 (Cat.# TA505452, Origene, Rockville, MD, USA), anti-phopho-GSK3β (Ser9) [Cat.# 9336, Cell Signaling Technology (CST), Beverly, MA, USA], anti-GSK3β [Cat.#, 9315;Cell Signaling Technology (CST), Beverly, MA, USA], a
Protocadherin 7-Associated Membranous Nephropathy
Sethi, Madden, Debiec et al
J Am Soc Nephrol (2021) 32 (5), 1249-1261 DOI: 10.1681/ASN.2020081165
Sethi, Madden, Debiec et al
J Am Soc Nephrol (2021) 32 (5), 1249-1261 DOI: 10.1681/ASN.2020081165
Cited by 5
AI Summary: OriGene’s anti-PCDH7 mouse monoclonal antibodies were used for Western blot analysis in this study to detect and confirm the presence of protocadherin 7 (PCDH7) protein in membranous nephropathy patient samples.
Snippet: Membranes were incubated overnight at 4°C with sera from patients, control subjects (dilution 1:50), and mouse mAbs (dilution 1:200) against PCDH7 (Origene). Subsequently, blots were washed and incubated for 2 hours at room temperature with goat anti-human or goat anti-mice IgG AP conjugate (both dilutions 1:10,000;Sigma). Immunoreactive proteins were visualized with 5-bromo-4-chloro-3-indolyl
Showing 1-3 of 3 papers.
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