GADD45G Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2F12]
$509.00
5 Days*
Specifications
| Product Data | |
| Clone Name | OTI2F12 |
|---|---|
| Application | IF, IHC, IP, WB |
| Recommended Dilution | WB 1:4000, IHC 1:150, IF 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human GADD45G(NP_006696) produced in HEK293T cell. |
| Buffer | PBS (pH 7.4) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 16.9 kDa |
| Gene Name | growth arrest and DNA damage inducible gamma |
| Database Link | |
| Background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. provided by RefSeq, Jul 2008 |
| Synonyms | CR6; DDIT2; GADD45gamma; GRP17 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Cell cycle, MAPK signaling pathway, p53 signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2F12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505437 | Carrier-free (BSA/glycerol-free) GADD45G mouse monoclonal antibody, clone OTI2F12 (formerly 2F12) | 100 ug |
$620.00
|
|
| TA505437 | GADD45G mouse monoclonal antibody, clone OTI2F12 (formerly 2F12) | 100 ul |
$447.00
|
|
| TA505437AM | GADD45G mouse monoclonal antibody,clone 2F12, Biotinylated | 100 ul |
$509.00
|
|
| TA505437S | GADD45G mouse monoclonal antibody, clone OTI2F12 (formerly 2F12) | 30 ul |
$200.00
|
|
Citations
Gadd45γ alleviates collagen-induced arthritis by increasing IL-10 level and suppressing JNK activity
Ma, Li, Yin et al
Int Immunopharmacol (2025) 151, 114329 DOI: 10.1016/j.intimp.2025.114329
Ma, Li, Yin et al
Int Immunopharmacol (2025) 151, 114329 DOI: 10.1016/j.intimp.2025.114329
Cited by 2
AI Summary: OriGene’s anti-Gadd45γ antibody (Cat No. TA505437) was used in this study to detect Gadd45γ protein levels, helping to elucidate its regulatory role in alleviating collagen-induced arthritis.
Snippet: saline (TBST) for 1 h at room temperature, the membranes were incubated with anti-Gadd45γ (OriGene: Cat No. TA505437), anti-JNK (Abcam: Cat No. EPR18841–95), anti-phosphor-JNK (Abcam: Cat No. EPR5693), anti-IL-10 (ThermoFisher, for mouse, Cat No. MA5–23796), anti-IL-10 (ThermoFisher, for human, Cat No. 14–7108-81) and anti-GAPDH (Abcam: Cat No. ab9485) or
GADD45γ induces G2/M arrest in human pharynx and nasopharyngeal carcinoma cells by cucurbitacin E
Hung, Chang, Lin et al
Sci Rep (2014) 4, 6454 DOI: 10.1038/srep06454
Hung, Chang, Lin et al
Sci Rep (2014) 4, 6454 DOI: 10.1038/srep06454
Cited by 11
AI Summary: OriGene’s anti-GADD45γ antibody (TA505437) was used in this study to detect GADD45γ protein levels, helping to demonstrate its role in CuE-induced G2/M cell cycle arrest in pharynx and nasopharyngeal carcinoma cells.
Snippet: Louis, MO, USA), anti-cyclin B1, anti-CDC2 (p34;sc-747), anti-p-CDC2 (p34 Tyr 15;sc-7989) (Santa Cruz BioTechnology, USA) and anti- GADD45γ (TA505437 OriGene Technologies, Rockville, MD, USA) antibodies for 1.5 ~ 2 hours. ... Cite SaveSaving
Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E
Hsu, Huang, Chen
Cell Death Dis (2014) 5, e1198 DOI: 10.1038/cddis.2014.151
Hsu, Huang, Chen
Cell Death Dis (2014) 5, e1198 DOI: 10.1038/cddis.2014.151
Cited by 40
AI Summary: In this study, the OriGene GADD45γ antibody (TA505437) was used to detect GADD45γ protein expression, helping to elucidate its role in CuE-induced G2/M cell cycle arrest in colorectal cancer cells.
Snippet: Briefly, 500 μg of cellular proteins were labeled using anti-cyclin B1 (SC-752, Santa Cruz BioTechnology) and GADD45γ (TA505437, OriGene Technologies, Rockville, MD, USA) following overnight incubation at room temperature. ... Cite SaveSaving
Inducement of mitosis delay by cucurbitacin E, a novel tetracyclic triterpene from climbing stem of Cucumis melo L., through GADD45γ in human brain malignant glioma (GBM) 8401 cells
Hsu, Chen, Huang
Cell Death Dis (2014) 5, e1087 DOI: 10.1038/cddis.2014.22
Hsu, Chen, Huang
Cell Death Dis (2014) 5, e1087 DOI: 10.1038/cddis.2014.22
Cited by 34
AI Summary: In this study, the OriGene GADD45γ antibody (TA505437) was used to detect and analyze the expression of GADD45γ protein, helping to demonstrate its role in cucurbitacin E-induced mitotic delay in human glioma cells.
Snippet: Briefly, 500 μg of cellular proteins were labeled using anti-CDC2 (Santa Cruz BioTechnology) and GADD45γ (TA505437 OriGene Technologies, Rockville, MD, USA) following overnight incubation at room temperature. The ... Cite SaveSaving
Showing 1-4 of 4 papers.
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