CD1C Mouse Monoclonal Antibody [Clone ID: OTI2D4]
$200.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2D4 |
|---|---|
| Application | IF, IHC |
| Recommended Dilution | IHC 1:150 IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CD1C(NP_001756) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 35.7 kDa |
| Gene Name | CD1c molecule |
| Database Link | |
| Background | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. provided by RefSeq |
| Synonyms | BDCA1; CD1; CD1A; R7 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2D4" antibodies (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505385 | Carrier-free (BSA/glycerol-free) CD1C mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) | 100 ug |
$620.00
|
|
| TA505385 | CD1C mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) | 100 ul |
$447.00
|
|
| TA505385AM | CD1C mouse monoclonal antibody,clone 2D4, Biotinylated | 100 ul |
$509.00
|
|
| TA505385BM | CD1C mouse monoclonal antibody,clone 2D4, HRP conjugated | 100 ul |
$509.00
|
|
| TA600315 | CD1C mouse monoclonal capture antibody, validated for ELISA and Luminex assays | 100 ug |
$458.00
|
|
| TA700316 | CD1C biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays | 50 ug |
$494.00
|
|
Citations
NOT ALL ANTIBODIES HAVE BEEN CREATED EQUAL: Antibodies validated for routinely processed tissue seldom apply to frozen tissue sections
Bolognesi, Mascadri, Perego et al
bioRxiv (2020)
Bolognesi, Mascadri, Perego et al
bioRxiv (2020)
Snippet: g1 CD1A O10 SCBT yes 626957 + + neg conformational historic g1 CD1c 2F4 Origene yes 2623067 neg neg neg neg orthogonal g1 CD1c 2D4 Origene yes 2623049 neg neg neg neg orthogonal g1 CD1c UMAB46 Origene yes 2629056 neg neg neg neg peptide microarray, orthogonal g2A CD2 B-8 SCBT yes 2073673 neg neg neg neg g2A CD20 L26 Dako yes 2282030 + + + conserved historic
Showing 1-1 of 1 papers.
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