MAGEA4 Mouse Monoclonal Antibody [Clone ID: OTI1F9]
$200.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1F9 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | WB 1:4000, IHC 1:150 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human MAGEA4(NP_001011550) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from serum-free cell culture supernatant by affinity chromatography Protein A/G (from mouse hybridoma) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 34.7 kDa |
| Gene Name | MAGE family member A4 |
| Database Link | |
| Background | This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene. provided by RefSeq, Jul 2008 |
| Synonyms | CT1.4; MAGE-41; MAGE-X2; MAGE4; MAGE4A; MAGE4B |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
Reviews
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| Product Manuals |
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Resources
Other "OTI1F9" antibodies (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505362 | Carrier-free (BSA/glycerol-free) MAGEA4 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9) | 100 ug |
$620.00
|
|
| TA505362 | MAGEA4 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9) | 100 ul |
$447.00
|
|
| TA505362AM | MAGEA4 mouse monoclonal antibody,clone 1F9, Biotinylated | 100 ul |
$509.00
|
|
| TA505362BM | MAGEA4 mouse monoclonal antibody,clone 1F9, HRP conjugated | 100 ul |
$509.00
|
|
| TA600567 | MAGEA4 mouse monoclonal antibody, clone OTI1F9 | 100 ug |
$447.00
|
|
Citations
Identifying MAGE-A4-positive tumors for TCR T cell therapies in HLA-A∗02-eligible patients
Wang, Navenot, Rafail et al
Molecular Therapy - Methods & Clinical Development (2024) 32 (2), 101265 DOI: 10.1016/j.omtm.2024.101265
Wang, Navenot, Rafail et al
Molecular Therapy - Methods & Clinical Development (2024) 32 (2), 101265 DOI: 10.1016/j.omtm.2024.101265
Cited by 21
AI Summary: OriGene contributed to this study by providing the anti-MAGE-A4 monoclonal antibody (clone OTIF9, TA505362), which was used to stain tissue samples and identify MAGE-A4-positive tumors.
Snippet: Tissue blocks were cut as 4-μm thickness slides, pretreated in the 3 in 1 PT module with TRS low pH antigen retrieval solution (Dako-K8005) at 60°C for 2 h and then at 97°C for 20 min, and then stained on the Dako autostainer Link 48 platform with an anti-MAGE-A4 monoclonal antibody (clone OTIF9, Origene, TA505362, 10 μg/mL) and an IgG isotype control antibody (IgG2a, Sigma Aldrich, M9144, 10 μg/mL) for 30 min at room temperature (22°C–25°C),
Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial
Hong, Van Tine, Biswas et al
Nat Med (2023) 29 (1), 104-114 DOI: 10.1038/s41591-022-02128-z
Hong, Van Tine, Biswas et al
Nat Med (2023) 29 (1), 104-114 DOI: 10.1038/s41591-022-02128-z
Cited by 204
AI Summary: In this study, the OriGene MAGE-A4 antibody (TA505362) was used for immunohistochemistry (IHC) staining to detect MAGE-A4 expression in tumor biopsy tissues, enabling the assessment of target antigen presence for patient selection and response analysis.
Snippet: notated and analyzed using Indica Labs-ISH version 3.3.9 algorithm, with CD3 staining as the nuclear stain, resulting in CD3+ cell count and MAGE-A4 SPEAR percentage positivity. MAGE-A4 IHC MAGE-A4 (OriGene, TA505362) IHC staining was performed on 4-μm sections of FFPE biopsy tissues. Staining was performed and scored at a laboratory certified by the CLIA and accredited by the Belgian Accreditat
Cancer‑testis antigens are predominantly expressed in uterine leiomyosarcoma compared with non‑uterine leiomyosarcoma
Iura, Kohashi, Yasutake et al
Oncology Letters (2017) 15 (1), 441 DOI: 10.3892/ol.2017.7274
Iura, Kohashi, Yasutake et al
Oncology Letters (2017) 15 (1), 441 DOI: 10.3892/ol.2017.7274
Showing 1-3 of 3 papers.
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