EIF5A2 Mouse Monoclonal Antibody [Clone ID: OTI6G7]

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SKU
TA505100
EIF5A2 mouse monoclonal antibody, clone OTI6G7 (formerly 6G7)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI6G7
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human EIF5A2(NP_065123) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 16.6 kDa
Gene Name eukaryotic translation initiation factor 5A2
Database Link
Synonyms EIF-5A2; eIF5AII
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI6G7" antibodies (4)
SKU Description Size Price
CF505100 Carrier-free (BSA/glycerol-free) EIF5A2 mouse monoclonal antibody, clone OTI6G7 (formerly 6G7) 100 ug
$620.00
TA505100AM EIF5A2 mouse monoclonal antibody,clone 6G7, Biotinylated 100 ul
$509.00
TA505100BM EIF5A2 mouse monoclonal antibody,clone 6G7, HRP conjugated 100 ul
$509.00
TA505100S EIF5A2 mouse monoclonal antibody, clone OTI6G7 (formerly 6G7) 30 ul
$200.00

file-alt Citations

Bruton tyrosine kinase inhibitors preserve anti-CD19 chimeric antigen receptor T-cell functionality and reprogram tumor micro-environment in B-cell lymphoma
Luo, Li, Wu et al
Cytotherapy (2023) 25 (7), 739-749 DOI: 10.1016/j.jcyt.2023.03.005
Cited by 29
AI Summary: In this study, OriGene products—including the Human CD19 (NM_001770) cDNA clone (RC208447) and Human GAPDH (NM_002046) qPCR Primer Pair (HPH000001)—were used to assess gene expression and validate experimental findings related to the effects of Bruton tyrosine kinase inhibitors on CAR T-cell function and the tumor microenvironment in B-cell lymphoma.
New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape
Schultz, Sheldon, Xie et al
Biol Open (2023) 12 (3) DOI: 10.1242/bio.059647
Cited by 6
AI Summary: OriGene’s mouse anti-eIF5A2 antibody (TA505100) was used in this study to specifically detect eIF5A2 protein by western blot, enabling the authors to confirm the absence of hypusine modification in eIF5A2 in their mutant mouse models.
Snippet: … Primary antibodies, rabbit anti-Hypusine (ABS1064, Millipore), mouse anti-eIF5A2 (TA505100, Origene) and mouse anti-β-actin (SC-47778, Santa Cruz Biotechnology) were incubated overnight at 4°C in 5% BSA in Tris-buffered saline containing 0.1% Tween-20. The anti-hypusine antibody identifies;- The mouse anti-eIF5A2 antibody (TA505100, Origene) was tested to be specific for eIF5A2 protein only and did not detect eIF5A1 protein by western blot when using
WB
Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer
Kim, Schultz, Chandramouli et al
J Drug Target (2022)
AI Summary: OriGene’s eIF5A2 antibody (TA505100) was used to detect eIF5A2 protein levels, enabling the researchers to assess the effects of pharmacological treatments on hypusine biosynthesis and tumor activity in endometrial cancer.
Snippet: 1:1000 eIF5A2 (TA505100, Origene Technologies, Rockville, MD),
Showing 1-3 of 3 papers.
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