RTKN Mouse Monoclonal Antibody [Clone ID: OTI1A4]
Specifications
| Product Data | |
| Clone Name | OTI1A4 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human RTKN(NP_149035) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 61 kDa |
| Gene Name | rhotekin |
| Database Link | |
| Background | This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq |
| Synonyms | B5 |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1A4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF505051 | Carrier-free (BSA/glycerol-free) RTKN mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) | 100 ug |
$620.00
|
|
| TA505051AM | RTKN mouse monoclonal antibody,clone 1A4, Biotinylated | 100 ul |
$509.00
|
|
| TA505051BM | RTKN mouse monoclonal antibody,clone 1A4, HRP conjugated | 100 ul |
$509.00
|
|
| TA505051S | RTKN mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) | 30 ul |
$200.00
|
|
Citations
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