Syntenin (SDCBP) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2H6]
$509.00
5 Days*
Specifications
| Product Data | |
| Clone Name | OTI2H6 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SDCBP(NP_005616) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 32.3 kDa |
| Gene Name | syndecan binding protein |
| Database Link | |
| Background | The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq |
| Synonyms | MDA-9; MDA9; ST1; SYCL; TACIP18 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2H6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF504796 | Carrier-free (BSA/glycerol-free) SDCBP mouse monoclonal antibody, clone OTI2H6 (formerly 2H6) | 100 ug |
$620.00
|
|
| TA504796 | SDCBP (Syntenin) mouse monoclonal antibody, clone OTI2H6 (formerly 2H6) | 100 ul |
$447.00
|
|
| TA504796AM | SDCBP mouse monoclonal antibody,clone 2H6, Biotinylated | 100 ul |
$509.00
|
|
| TA504796S | SDCBP (Syntenin) mouse monoclonal antibody, clone OTI2H6 (formerly 2H6) | 30 ul |
$200.00
|
|
Citations
Role of Collection Media on the Biological Activity of Extracellular Vesicles From hTERT-Immortalised Mesenchymal Stromal Cells
Brancolini, Bobbili, Wieser et al
J Extracell Vesicles (2026) 15 (5), e70298 DOI: 10.1002/jev2.70298
Brancolini, Bobbili, Wieser et al
J Extracell Vesicles (2026) 15 (5), e70298 DOI: 10.1002/jev2.70298
AI Summary: OriGene’s Syntenin-1 antibody (TA504796) was used in this study to characterize extracellular vesicles from hTERT-immortalised mesenchymal stromal cells, helping assess the impact of different collection media on EV properties.
Snippet: h). The following primary antibodies were used: TSG101, abcam, ab125011, 1:1,000;Syntenin-1, Origene, TA504796, 1:1,000;Calnexin, GeneTex, GTX101676, 1:1000, CD81 (B-11), Santa Cruz, sc-16602. The membrane was washed three times with TBS (Thermo Fisher Scientific) mixed with 0.1% Tween-20 (TBS-T) before being incubated with the relevant secondary antibo
Immortalization of mesenchymal stromal cells by hTERT does not affect the functional properties of secreted extracellular vesicles
Brancolini, Bobbili, Pultar et al
J Biotechnol (2026) 414, 124-145 DOI: 10.1016/j.jbiotec.2026.03.010
Brancolini, Bobbili, Pultar et al
J Biotechnol (2026) 414, 124-145 DOI: 10.1016/j.jbiotec.2026.03.010
Cited by 9
AI Summary: In this study, OriGene's Syntenin-1 antibody (TA504796) was used to analyze extracellular vesicle markers, helping to assess whether hTERT immortalization affects the properties of mesenchymal stromal cell-derived extracellular vesicles.
Snippet: The following primary antibodies were used: TSG101, abcam, ab125011, 1:1000;Syntenin-1, Origene, TA504796, 1:1000;Calnexin, GeneTex, GTX101676, 1:1000, CD81 (B-11), Santa Cruz, sc-16602
Native extracellular vesicles display surface bound RNAs that are co-delivered to cells
Weissinger, Bobbili, Yan et al
bioRxiv (2025)
Weissinger, Bobbili, Yan et al
bioRxiv (2025)
Cited by 3
AI Summary: In this study, the OriGene Syntenin-1 antibody (TA504796) was used for immunoblotting to analyze protein markers associated with extracellular vesicles, contributing to the characterization of EV surface components.
Snippet: The membranes were blocked with 50% Intercept (TBS) Blocking Buffer (LI-COR) 50% TBS supplemented with 0.1% Tween-20 (Sigma Aldrich) for 1 h at room temperature. After blocking, the membranes were incubated overnight at 4ºC with primary antibody solution prepared in 50% Intercept (TBS) Blocking buffer (TSG101, abcam, ab125011, 1:2000;Syntenin-1, Origene, TA504796, 1:1000;Calnexin, abcam, ab22595, 1:1000)
Rapid extracellular vesicle surface decoration with targeting moieties based on a fluorescein binding single chain variable fragment snorkel
Roefs, Gamauf, Kroenigsberger et al
J Control Release (2025) 390, 114558 DOI: 10.1016/j.jconrel.2025.114558
Roefs, Gamauf, Kroenigsberger et al
J Control Release (2025) 390, 114558 DOI: 10.1016/j.jconrel.2025.114558
Cited by 3
AI Summary: OriGene's Syntenin-1 antibody (#TA504796) was used to detect and analyze Syntenin-1 protein levels in extracellular vesicles, contributing to the characterization of EVs in this study.
Snippet: Santa Cruz, #sc-166029);CD9 (1:500, Merck Millipore, #CBL162, non-reduced), CD63 (1:1000, Invitrogen, #10628D,), Syntenin-1 (1:1000, Origene, #TA504796);GAPDH (1:2000, Cell signaling, #2118);TSG101 (1:1000, Abcam, #ab125011);FLAG (1:5000, Sigma Aldrich, #F3165), HA (1:2000, Cell signaling, #3724), cMyc (1:1000, Cell signaling, #2276)
Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles
Zheng, Mowoe, Hou et al
Adv Sci (Weinh) (2025)
Zheng, Mowoe, Hou et al
Adv Sci (Weinh) (2025)
Cited by 2
AI Summary: In this study, the OriGene anti-Syntenin-1 antibody (TA504796) was used for immunoblotting to detect and analyze EV-associated proteins, contributing to the characterization of extracellular vesicle surface proteins.
Snippet: The membrane was immersed in blocking buffer (LI-COR, 927–60004) for 1 h at room temperature and incubated with primary antibodies (1:1000 dilution for anti-Calnexin [ThermoFisher, PA5-19169], anti-Syntenin-1 [Origene, TA504796], Streptavidin-680RD [926-68079, LI-COR]) overnight at 4 °C
Surface display of proximity labeling enzymes on extracellular vesicles for surfaceome and target cell mapping
Zheng, Mowoe, Hou et al
bioRxiv (2024)
Zheng, Mowoe, Hou et al
bioRxiv (2024)
Cited by 1
Snippet: n [ThermoFisher, PA5-19169], anti466 Syntenin-1 [Origene, TA504796], Streptavidin-680RD [926-68079, LI-COR]) overnight at 4 ℃. 467 Afterwards, the membrane was rinsed using TBS supplemented with 0.1% Tween 20 (TBS-T) 468 for 3 times and stained with corresponding secondary antibodies (925-68070, 926-32350, 469 LI-COR;1:10,000 dilution) for 1 h at RT. …
Showing 1-6 of 28 papers.
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