PALS1 Mouse Monoclonal Antibody [Clone ID: OTI2D3]

SKU TA504451

MPP5 mouse monoclonal antibody, clone OTI2D3 (formerly 2D3)

Product Data

• Clone Name: OTI2D3
• Application: FC, WB
• Recommended Dilution: WB 1:500~2000, FLOW 1:100
• Reactivity: Dog, Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human MPP5(NP_071919) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.88 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 77.1 kDa
• Gene Name: protein associated with LIN7 1, MAGUK family member
• Database Link:
  NP_071919
  Q8N3R9
• Background: This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
• Synonyms: PALS1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Tight junction