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SEC14 like protein 2 (SEC14L2) Mouse Monoclonal Antibody [Clone ID: OTI4H2]

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SKU
TA503723
SEC14L2 ( SEC14-like 2) mouse monoclonal antibody, clone OTI4H2 (formerly 4H2)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
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View other "SEC14 like protein 2 or NM_012429" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4H2
Application FC, IF, IHC, WB
Recommended Dilution WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human SEC14L2(NP_036561) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration Lot dependent
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 46 kDa
Gene Name SEC14 like lipid binding 2
Database Link
Background This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. provided by RefSeq
Synonyms C22orf6; SPF; TAP; TAP1
Reference Data
Protein Categories Intracellular Proteins
Protein Families Transcription Factors
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Other "OTI4H2" antibodies (4)
SKU Description Size Price
CF503723 Carrier-free (BSA/glycerol-free) SEC14L2 mouse monoclonal antibody, clone OTI4H2 (formerly 4H2) 100 ug
$620.00
TA503723AM SEC14L2 ( SEC14-like 2) mouse monoclonal antibody, clone OTI4H2 (formerly 4H2), Biotinylated 100 ul
$509.00
TA503723BM SEC14L2 ( SEC14-like 2) mouse monoclonal antibody, clone OTI4H2 (formerly 4H2), HRP conjugated 100 ul
$509.00
TA503723S SEC14L2 ( SEC14-like 2) mouse monoclonal antibody, clone OTI4H2 (formerly 4H2) 30 ul
$200.00

file-alt Citations

The ORP9-ORP11 dimer promotes sphingomyelin synthesis
Cabukusta, Borst Pauwels, Akkermans et al
Elife (2024) 12 DOI: 10.7554/eLife.91345
AI Summary: In this study, the OriGene SEC14L2 antibody (catalog #26983–1-AP) was used to investigate the role of lipid transfer proteins in cellular lipid regulation, contributing to the identification of the ORP9-ORP11 dimer’s function in promoting sphingomyelin synthesis.
Snippet: h 11879–1-AP Rabbit STARD7 Proteintech 15689–1-AP Rabbit SEC14L1 Proteintech 25541–1-AP Rabbit PITNM1 Proteintech 26983–1-AP Rabbit SEC14L2 Origene TA503723 Mouse TEX2 Bethyl A304-705A Rabbit FAPP2 Proteintech 15410–1-AP Rabbit ORP9 Santa Cruz sc-398961 Mouse CD63-V450 BD Horizon 56
FigureFigureFigure
FC
A Golgi-derived vesicle potentiates PtdIns4P to PtdIns3P conversion for endosome fission
Gong, Guo, Ding et al
Nat Cell Biol (2021) 23 (7), 782-795 DOI: 10.1038/s41556-021-00704-y
Cited by 39
AI Summary: In this paper, the OriGene SEC14L2 antibody (TA503723) was used for western blotting and immunostaining to detect SEC14L2 protein, thereby facilitating the study of its role in endosome fission.
Snippet: Several commercial antibodies and chemicals were used in this paper, including SEC14L2 (TA503723, ORIGENE;1:1,000 for western blotting, 1:100 for immunostaining), Myc (sc-40AC, Santa Cruz;1:1,000 for western blotting, 1:100 for immunoprecipitation), Flag (F1804, Sigma;1:1,000 for western blotting, 1:100 for immunostaining), GFP (sc-9996, Santa Cruz;1:100 for immunostaining), phalloidin (p1951, Sigma;1:500 for immunostaining), EEA1 (3288, Cell Signaling Technology;1:100 for immunostaining)
WB IF IP
Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis
Gong, Li, Xiao et al
Nat Commun (2019) 10 (1), 1606 DOI: 10.1038/s41467-019-09604-0
AI Summary: OriGene’s SEC14L2 antibody (TA503723) was used for immunofluorescence experiments to investigate the role of SEC14L2 in VEGFR2 signaling and trafficking in this study.
Snippet: times to remove un-internalized anti-VEGFR2 antibody on the cell surface. After wash, cells were fixed by 4% PF and subjected for immunofluorescence. Antibodies used here including SEC14L2 (TA503723, ORIGENE, 1:100), EEA1 (#3288, Cell Signaling Technology, 1:100), VEGFR2 (#2479, Cell Signaling Technology, 1:200) and CD63 (#CBL553, Millipore, 1:100). To measure the recycling of VEGF2, transfected
FigureFigureFigure
IF
The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca(2+) signaling
Gong, Shen, Xiao et al
Elife (2017) 6 DOI: 10.7554/eLife.26362
AI Summary: OriGene’s mouse anti-SEC14L2 antibody (TA503723) was used in this study to detect SEC14L2 protein, enabling the authors to investigate its role in mediating Wnt/Ca(2+) signaling.
Snippet: rabbit anti-p-Erk (Thr202/Tyr204) (Cell Signaling Technology, Danvers, MA, #9101, RRID:AB_331646), rabbit anti-p-Akt (Ser473) (Cell Signaling Technology, #4060, RRID:AB_2315049), mouse anti-SEC14L2 (ORIGENE, Rockville, MD, TA503723, RRID:AB_11126641), phalloidin (Sigma, St. Louis, MO, p1951, RRID:AB_2315148)
FigureFigureFigure
WB
SEC14L2 enables pan-genotype HCV replication in cell culture
Saeed, Andreo, Chung et al
Nature (2015) 524 (7566), 471-5 DOI: 10.1038/nature14899
Cited by 132
AI Summary: OriGene contributed to this study by providing the SEC14L2 mouse monoclonal antibody clone 4H2, which was used to detect SEC14L2 protein expression during experiments investigating its role in enabling pan-genotype HCV replication in cell culture.
Snippet: The GIPZ Human Whole Genome shRNA library (no. RHS6037) was also from GE Healthcare. The following primary antibodies were used in this study: SEC14L2 mouse monoclonal antibody clone 4H2 (Origene, MD), SEC14L2 rabbit polyclonal antibody (Acris Antibodies, CA),
Showing 1-5 of 5 papers.
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