PDE4 (PDE4B) Mouse Monoclonal Antibody [Clone ID: OTI2B6]

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SKU
TA503439
PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI2B6
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.91 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 83.2 kDa
Gene Name phosphodiesterase 4B
Database Link
Background This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq
Synonyms DPDE4; PDE4B5; PDEIVB
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Progesterone-mediated oocyte maturation, Purine metabolism
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Other "OTI2B6" antibodies (4)
SKU Description Size Price
CF503439 Carrier-free (BSA/glycerol-free) PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) 100 ug
$620.00
TA503439AM PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6), Biotinylated 100 ul
$509.00
TA503439BM PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6), HRP conjugated 100 ul
$509.00
TA503439S PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) 30 ul
$200.00

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