PDE4 (PDE4B) Mouse Monoclonal Antibody [Clone ID: OTI2B6]
Specifications
| Product Data | |
| Clone Name | OTI2B6 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.91 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 83.2 kDa |
| Gene Name | phosphodiesterase 4B |
| Database Link | |
| Background | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq |
| Synonyms | DPDE4; PDE4B5; PDEIVB |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI2B6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF503439 | Carrier-free (BSA/glycerol-free) PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) | 100 ug |
$620.00
|
|
| TA503439AM | PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6), Biotinylated | 100 ul |
$509.00
|
|
| TA503439BM | PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6), HRP conjugated | 100 ul |
$509.00
|
|
| TA503439S | PDE4B mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) | 30 ul |
$200.00
|
|
Citations
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