LGR5 Mouse Monoclonal Antibody [Clone ID: OTI2A2]
$200.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2A2 |
|---|---|
| Application | FC, IF, IHC, IP, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100, IP 2ug/500ul |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in HEK293T Cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 99.8 kDa |
| Database Link | |
| Synonyms | FEX; GPR49; GPR67; GRP49; HG38 |
| Reference Data | |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
Reviews
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| FAQs |
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Resources
Citations
Parabacteroides distasonis ameliorates ETEC-induced diarrhea in weaned piglets by regulating intestinal barrier function and intestinal inflammation
Wu, Zhang, Li et al
Porcine Health Manag (2026)
Wu, Zhang, Li et al
Porcine Health Manag (2026)
AI Summary: In this study, the OriGene product Lgr5 antibody (TA503316) was used to assess intestinal epithelial proliferation, contributing to the evaluation of how Parabacteroides distasonis ameliorates ETEC-induced diarrhea in weaned piglets by enhancing intestinal barrier function and reducing inflammation.
From Patient Liver Tissue to Organoids: Establishment of a Translational Platform Using Healthy, Steatotic, and Cirrhotic Tissue Sources
Pohlberger, Hardt, Kühnel et al
Cells (2026) 15 (5) DOI: 10.3390/cells15050432
Pohlberger, Hardt, Kühnel et al
Cells (2026) 15 (5) DOI: 10.3390/cells15050432
Cited by 4
AI Summary: In this study, the OriGene mouse LGR5 antibody (#TA503316) was used for immunofluorescence staining to identify liver progenitor cell features within patient-derived liver organoids, aiding in the characterization of organoid cellular composition.
Snippet: use Albumin (1:400, #ab236492, Abcam), mouse CK19 (1:600, #ab7755, Abcam), mouse HNF4α (1:500, #ab41898, Abcam), mouse Ki67 (1:500, #M7240, Dako, Santa Clara, CA, USA), mouse LGR5 (1:500, #TA503316, Origene, Rockville, MD, USA), rabbit collagen I (1:400, #CL50151AP, Cedarlane, Burlington, Canada), and rabbit α-SMA (1:200, #ab124964, Abcam). After removing paraffin, antibody retrieval was perform
Thyroid hormone inactivation sustains cancer stem cell maintenance and tumorigenesis in basal cell carcinoma
Di Girolamo, Di Cicco, Miro et al
J Invest Dermatol (2026)
Di Girolamo, Di Cicco, Miro et al
J Invest Dermatol (2026)
Cited by 2
Targeting of the m6A eraser ALKBH5 suppresses stemness and chemoresistance of colorectal cancer
Zhou, Chen, Liu et al
Nat Commun (2025) 17 (1), 803 DOI: 10.1038/s41467-025-67502-0
Zhou, Chen, Liu et al
Nat Commun (2025) 17 (1), 803 DOI: 10.1038/s41467-025-67502-0
Cited by 9
AI Summary: OriGene’s LGR5 antibody (#TA503316) was used at a 1:200 dilution for immunostaining human tissue microarrays to assess stem cell marker expression in this study on colorectal cancer.
Snippet: The slides were blocked by goat serum. The dilutions for ALKBH5 (HPA001796, Sigma-Aldrich) were diluted as 1:500, FAM84A (sc-101207, Santa Cruz Biotechnology) were diluted as 1:200, CD133 (#5860, CST), LGR5 (#TA503316, Origene) were diluted as 1:200 for human tissue microarray
Development of an in vitro platform for nutrient absorption studies as an alternative to in vivo pig models
Lee, Jung, Ock et al
Journal of Animal Science and Technology (2025)
Lee, Jung, Ock et al
Journal of Animal Science and Technology (2025)
TSC2/mTORC1 integrates deoxynivalenol signals recognized by membrane receptors IR and EGFR to restrict intestinal stem cell function
Dou, Qu, Qin et al
J Hazard Mater (2025) 494, 138769-138769 DOI: 10.1016/j.jhazmat.2025.138769
Dou, Qu, Qin et al
J Hazard Mater (2025) 494, 138769-138769 DOI: 10.1016/j.jhazmat.2025.138769
Cited by 8
AI Summary: OriGene’s Lgr5 antibody (#TA503316) was used in this study to detect intestinal stem cell marker expression, contributing to the analysis of how DON affects ISC function via the TSC2/mTORC1 pathway.
Snippet: to detect signals using FluorChem M imaging system (ProteinSimple, Inc., Santa Clara, CA, USA). Antibodies against Lgr5 (1:1000;#TA503316, OriGene Technologies, MD, USA), KRT20 (1:1000;#13063, Cell Signaling Technology, BSN, USA), IR (1:1000;#sc81465, Santa Cruz Biotechnology, CA, USA), EGFR (1:1000;#4267, Cell Signaling Technology, BSN, USA), S6K1 (1:1000;#34475, Cell Signaling
Showing 1-6 of 49 papers.
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