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PTP1B (PTPN1) Mouse Monoclonal Antibody [Clone ID: OTI1C5]

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SKU
TA503309
PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

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View other "PTP1B or NM_002827" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1C5
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PTPN1(NP_002818) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.87 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 49.8 kDa
Gene Name protein tyrosine phosphatase non-receptor type 1
Database Link
Background The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. provided by RefSeq
Synonyms PTP1B
Reference Data
Protein Categories Growth Factors, Membrane Proteins
Protein Families Druggable Genome, Phosphatase, Transmembrane
Protein Pathways Adherens junction, Insulin signaling pathway
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Other "OTI1C5" antibodies (4)
SKU Description Size Price
CF503309 Carrier-free (BSA/glycerol-free) PTPN1 mouse monoclonal antibody, clone OTI1C5 (formerly 1C5) 100 ug
$620.00
TA503309AM PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5), Biotinylated 100 ul
$509.00
TA503309BM PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5), HRP conjugated 100 ul
$509.00
TA503309S PTPN1 (PTP1B) mouse monoclonal antibody, clone OTI1C5 (formerly 1C5) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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