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RGS5 Mouse Monoclonal Antibody [Clone ID: OTI1C1]

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SKU
TA503075
RGS5 mouse monoclonal antibody, clone OTI1C1 (formerly 1C1)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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Frequently Bought Together (2)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
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LY418548 Transient overexpression lysate of regulator of G-protein signaling 5 (RGS5) (as WB positive control) 100 ug
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View other "RGS5 or NM_003617" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1C1
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RGS5 (NP_003608) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 20.8 kDa
Gene Name regulator of G protein signaling 5
Database Link
Background This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129
Note WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "OTI1C1" antibodies (4)
SKU Description Size Price
CF503075 Carrier-free (BSA/glycerol-free) RGS5 mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) 100 ug
$620.00
TA503075AM RGS5 mouse monoclonal antibody, clone 1C1, Biotinylated 100 ul
$509.00
TA503075BM RGS5 mouse monoclonal antibody, clone 1C1, HRP conjugated 100 ul
$509.00
TA503075S RGS5 mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) 30 ul
$200.00

file-alt Citations

Single-cell RNA-seq recognized the initiator of epithelial ovarian cancer recurrence
Kan, Zhang, Zhou et al
Oncogene (2022)
Cited by 71
AI Summary: OriGene's Anti-mouse RGS5 antibody (TA503075) was used in this study to detect RGS5 protein expression, helping to identify and characterize cancer-associated fibroblast subpopulations involved in epithelial ovarian cancer recurrence.
Snippet: Anti-mouse RGS5 (TA503075, OriGene, Rockville, MD) and anti-rabbit CYR61 (ab10760, Abcam) primary antibodies were used for the detection of target proteins
Ex vivo intact tissue analysis reveals alternative calcium-sensing behaviors in parathyroid adenomas
Koh, Zhang, Roman et al
J Clin Endocrinol Metab (2021)
Cited by 7
AI Summary: OriGene contributed to this study by providing the anti-RGS5 monoclonal antibody (catalog number TA503075S), which was used to evaluate the expression of RGS5 as part of the investigation into mechanisms underlying altered calcium sensing in parathyroid adenomas.
Snippet: generated and kindly provided to us by Dr. Wenhan Chang of UCSF) (1 ug/ml in blocking solution), anti-RGS5 monoclonal antibody (Origene, catalog number TA503075S;1:1000 in blocking solution), anti-RCAN1 polyclonal
Pro-angiogenic Activity Discriminates Human Adipose-Derived Stromal Cells From Retinal Pericytes: Considerations for Cell-Based Therapy of Diabetic Retinopathy
Kremer, Gebauer, Elvers-Hornung et al
Front Cell Dev Biol (2020) 8, 387 DOI: 10.3389/fcell.2020.00387
Cited by 19
AI Summary: OriGene Technologies' mouse anti-human RGS5 antibody (clone OTI1C1) was used in this study to identify and characterize pericyte markers, contributing to the comparison of adipose-derived stromal cells and retinal pericytes.
Snippet: to-use mouse anti-human α-SMA (Progen, Heidelberg, Germany), mouse anti-human NG-2 (1:100;Santa Cruz Biotechnology), mouse anti-human RGS5 (RGS5 and RGS5-AF647 clone B4, 1:100;Santa Cruz Biotechnology or clone OTI1C1;OriGene Technologies
FigureFigureFigure
FC
Brain pericytes acquire a microglial phenotype after stroke
Ozen, Deierborg, Miharada et al
Acta Neuropathol. (2014)
Cited by 213
AI Summary: In this study, the OriGene mouse anti-RGS5 antibody was used to identify and track pericytes, helping demonstrate their activation and phenotypic shift to microglia-like cells after stroke.
Snippet: rabbit, Page 3. Acta Neuropathol 1 3 Abcam), Ng2 (1:500, rabbit, Chemicon), IBA1 (1:2,000, rab- bit, Wako), anti-Ki67 (1:100, rabbit, Novacostra), anti- PDgFrβ (1:200, rabbit, cell signaling), rgS5 (1:200, mouse, OrIgeNe). After ... Cite SaveSaving
IHC
Lipid rafts are required for signal transduction by AGTR1 in neonatal glomerular mesangial cells
Adebiyi, Soni, John et al
Exp. Cell Res. (2014)
Cited by 23
AI Summary: OriGene's mouse monoclonal anti-RGS5 antibody (TA503075) was used in this study to detect RGS5 protein expression, contributing to the analysis of signaling components involved in AGTR1-mediated pathways in neonatal glomerular mesangial cells.
Snippet: Mouse monoclonal anti-CAV-1 (sc-53564), mouse monoclonal anti-RGS5 (TA503075), and rabbit monoclonal anti-CYK18 (AJ1223) antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA), Origene Technologies (Rockville, MD), and Abgent Inc ... Cite SaveSaving
Showing 1-5 of 5 papers.
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