ADH1B Mouse Monoclonal Antibody [Clone ID: OTI4F12]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI4F12 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100 |
| Reactivity | Dog, Human, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ADH1B (NP_000659) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.89 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 39.7 kDa |
| Gene Name | alcohol dehydrogenase 1B (class I), beta polypeptide |
| Database Link | |
| Background | The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. provided by RefSeq |
| Synonyms | ADH2; HEL-S-117 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4F12" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502777 | Carrier-free (BSA/glycerol-free) ADH1B mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) | 100 ug |
$620.00
|
|
| TA502777AM | ADH1B mouse monoclonal antibody, clone OTI4F12 (formerly 4F12), Biotinylated | 100 ul |
$509.00
|
|
| TA502777BM | ADH1B mouse monoclonal antibody, clone OTI4F12 (formerly 4F12), HRP conjugated | 100 ul |
$509.00
|
|
| TA502777S | ADH1B mouse monoclonal antibody, clone OTI4F12 (formerly 4F12) | 30 ul |
$200.00
|
|
Citations
Further evidence supporting a potential role for ADH1B in obesity
Morales, Cromack, Tripathy et al
Sci Rep (2021) 11 (1), 1932 DOI: 10.1038/s41598-020-80563-z
Morales, Cromack, Tripathy et al
Sci Rep (2021) 11 (1), 1932 DOI: 10.1038/s41598-020-80563-z
Cited by 27
AI Summary: OriGene's anti-ADH1A antibody was used in this study to detect ADH1A protein levels, contributing to the analysis of alcohol dehydrogenase family members in relation to obesity and insulin resistance.
Snippet: pore (St. Louis, MO) and diluted in medium as needed. Anti-ADH1B, anti-ADH1C, anti-FABP4, and anti-adiponectin antibodies were purchased from Abcam Inc. (Cambridge, MA). Anti-ADH1A was purchased from Origene Technologies, Inc. (Rockville, MD). Anti-DDK, anti-Akt, anti-Phospho-Akt, and anti-PPARγ were purchased from Cell Signaling (Danvers, MA). Anti-GLUT4 was purchased form Bioss, Inc (Boston, MA
Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers
Samak, Gangwar, Meena et al
Sci Rep (2016) 6, 38899 DOI: 10.1038/srep38899
Samak, Gangwar, Meena et al
Sci Rep (2016) 6, 38899 DOI: 10.1038/srep38899
AI Summary: OriGene products contributed to this study by providing anti-ADH1B and anti-ALDH2 antibodies, which were used to detect and analyze the expression of alcohol dehydrogenase and aldehyde dehydrogenase in Caco-2 cells.
Snippet: Anti-ZO-1 and anti-occludin antibodies were purchased from Invitrogen (Carlsbad, CA). Anti ADH1B and anti-ALDH2 antibodies were procured from Origene Technologies (Atlanta, GA)
Showing 1-2 of 2 papers.
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