IKB zeta (NFKBIZ) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1E8]

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TA502768BM
NFKBIZ mouse monoclonal antibody, clone 1E8, HRP conjugated
  $509.00
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Specifications
Specifications
Product Data
Clone Name OTI1E8
Application FC, WB
Recommended Dilution WB 1:500, FLOW 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NFKBIZ (NP_113607) produced in E.coli.
Buffer PBS (pH 7.4) containing 1% BSA and 50% glycerol
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 77.9 kDa
Gene Name NFKB inhibitor zeta
Database Link
Background This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq
Synonyms IKBZ; INAP; MAIL
Note WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome
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Other "OTI1E8" antibodies (5)
SKU Description Size Price
CF502768 Carrier-free (BSA/glycerol-free) NFKBIZ mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 100 ug
$620.00
TA502768 NFKBIZ mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 100 ul
$447.00
TA502768AM NFKBIZ mouse monoclonal antibody, clone 1E8, Biotinylated 100 ul
$509.00
TA502768HM NFKBIZ mouse monoclonal antibody, clone 1E8, PE conjugated 100 ul
$509.00
TA502768S NFKBIZ mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 30 ul
$200.00

file-alt Citations

NOX1 drives inflammatory bowel disease through oxidant-dependent stabilization of IκBζ
Song, Pintard, Pelletier et al
Free Radic Biol Med (2026) 255, 289-306 DOI: 10.1016/j.freeradbiomed.2026.07.037
Cited by 1
AI Summary: In this study, OriGene’s mouse anti-IκBζ antibody (TA502768) was used to detect IκBζ protein levels, helping to elucidate the role of NOX1 in stabilizing IκBζ and sustaining inflammation in inflammatory bowel disease.
Snippet: Rabbit and mice antibodies directed against IκBζ (# 9244S;#93726;#TA502768) were from Cell Signaling Technology (Leiden, The Netherlands) and OriGene (Herford, Germany) respectively
A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture
Zheng, Turton, Zhu et al
Oncogenesis (2016) 5, e184
AI Summary: In this study, the OriGene product NFKBIZ antibody (TA502768S) was used to detect NFKBIZ protein levels, contributing to the investigation of molecular mechanisms underlying the survival of activated B-cell-like diffuse large B-cell lymphoma cells.
Snippet: α (9D8, ab119352, from Abcam, Cambridge, MA, USA), anti-STAT3β, 27 anti-phospho-STAT3 (Tyr-705) (D3A7) (#9145, from Cell Signaling Technology), anti-NFKBIA (L35A5, from Cell Signaling Technology), anti-NFKBIZ (TA502768S, from OriGene Technologies, ... Cite SaveSaving
Showing 1-2 of 2 papers.
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