ATP6V1B1 Mouse Monoclonal Antibody [Clone ID: OTI2D2]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2D2 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | WB 1:500~2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ATP6V1B1 (NP_001683) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.47 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 56.7 kDa |
| Gene Name | ATPase H+ transporting V1 subunit B1 |
| Database Link | |
| Background | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. provided by RefSeq |
| Synonyms | ATP6B1; RTA1B; VATB; VMA2; VPP3 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2D2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502667 | Carrier-free (BSA/glycerol-free) ATP6V1B1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) | 100 ug |
$620.00
|
|
| TA502667AM | ATP6V1B1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), Biotinylated | 100 ul |
$509.00
|
|
| TA502667BM | ATP6V1B1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), HRP conjugated | 100 ul |
$509.00
|
|
| TA502667S | ATP6V1B1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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