NNMT Mouse Monoclonal Antibody [Clone ID: OTI3D8]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI3D8 |
|---|---|
| Application | FC, IF, IHC, Simple Western, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100; Simple Western 1:20-1:50 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human NNMT(NP_006160) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 29.4 kDa |
| Gene Name | nicotinamide N-methyltransferase |
| Database Link | |
| Background | N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. provided by RefSeq |
| Synonyms | nicotinamide N-methyltransferase |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Metabolic pathways, Nicotinate and nicotinamide metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3D8" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502624 | Carrier-free (BSA/glycerol-free) NNMT mouse monoclonal antibody, clone OTI3D8 (formerly 3D8) | 100 ug |
$620.00
|
|
| TA502624AM | NNMT mouse monoclonal antibody, clone OTI3D8 (formerly 3D8), Biotinylated | 100 ul |
$509.00
|
|
| TA502624BM | NNMT mouse monoclonal antibody, clone OTI3D8 (formerly 3D8), HRP conjugated | 100 ul |
$509.00
|
|
| TA502624S | NNMT mouse monoclonal antibody, clone OTI3D8 (formerly 3D8) | 30 ul |
$200.00
|
|
Citations
NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment
Ghezzi, Fiorilla, Carreira et al
Cell Commun Signal (2025) 23 (1), 348 DOI: 10.1186/s12964-025-02361-2
Ghezzi, Fiorilla, Carreira et al
Cell Commun Signal (2025) 23 (1), 348 DOI: 10.1186/s12964-025-02361-2
Cited by 9
AI Summary: In this study, OriGene's NNMT antibody (#TA502624) was used to detect and analyze NNMT expression in melanoma cells, contributing to the identification of NNMT as a key mediator of BRAF inhibitor resistance and its release via extracellular vesicles.
Snippet: were used: NAMPT (Bethyl Laboratories, #A300-779 A, Montgomery, Texas, USA);NNMT #E6N22 and Phospho-NF-κB p65 (Ser536) #3033 (both from Cell Signaling Technology, Danvers, Massachusetts, USA;and OriGene Technologies, #TA502624, Rockville, MD, USA);TSG101 #GTX70255 and Vimentin #GTX100619 (both from GeneTex, Irvine, CA, USA);CD9 ab236630;Calnexin ab22595 and Syntenin ab133267 (all from Abca
Showing 1-1 of 1 papers.
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