HDAC6 Mouse Monoclonal Antibody [Clone ID: OTI3E7]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI3E7 |
|---|---|
| Application | FC, IHC, Simple Western, WB |
| Recommended Dilution | WB 1:500~1000, IHC 1:150, FLOW 1:100 ; Simple Western 1:20-1:50 |
| Reactivity | Human, Monkey |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.61 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 131.2 kDa |
| Gene Name | histone deacetylase 6 |
| Database Link | |
| Background | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. provided by RefSeq |
| Synonyms | CPBHM; HD6; JM21; PPP1R90 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3E7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502177 | Carrier-free (BSA/glycerol-free) HDAC6 mouse monoclonal antibody, clone OTI3E7 (formerly 3E7) | 100 ug |
$620.00
|
|
| TA502177AM | HDAC6 mouse monoclonal antibody, clone OTI3E7 (formerly 3E7), Biotinylated | 100 ul |
$509.00
|
|
| TA502177BM | HDAC6 mouse monoclonal antibody, clone OTI3E7 (formerly 3E7), HRP conjugated | 100 ul |
$509.00
|
|
| TA502177S | HDAC6 mouse monoclonal antibody, clone OTI3E7 (formerly 3E7) | 30 ul |
$200.00
|
|
Citations
HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma
Wang, Hu, Tang et al
Cancer Lett (2016) 379 (1), 134-42 DOI: 10.1016/j.canlet.2016.06.001
Wang, Hu, Tang et al
Cancer Lett (2016) 379 (1), 134-42 DOI: 10.1016/j.canlet.2016.06.001
Cited by 120
HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells
Wang, Hu, Tang et al
Med. Oncol. (2016) 33 (5), 50 DOI: 10.1007/s12032-016-0765-5
Wang, Hu, Tang et al
Med. Oncol. (2016) 33 (5), 50 DOI: 10.1007/s12032-016-0765-5
Cited by 29
Showing 1-2 of 2 papers.
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