ERK5 (MAPK7) Mouse Monoclonal Antibody [Clone ID: OTI2E2]
Specifications
| Product Data | |
| Clone Name | OTI2E2 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | WB 1:2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human MAPK7 (NP_002740) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.74 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 88.2 kDa |
| Gene Name | mitogen-activated protein kinase 7 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. provided by RefSeq |
| Synonyms | BMK1; ERK4; ERK5; PRKM7 |
| Reference Data | |
| Protein Categories | Cytokines, Enzyme: Kinases, Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Gap junction, GnRH signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2E2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502148 | Carrier-free (BSA/glycerol-free) MAPK7 mouse monoclonal antibody, clone OTI2E2 (formerly 2E2) | 100 ug |
$620.00
|
|
| TA502148AM | MAPK7 (ERK5) mouse monoclonal antibody, clone OTI2E2 (formerly 2E2), Biotinylated | 100 ul |
$509.00
|
|
| TA502148BM | MAPK7 (ERK5) mouse monoclonal antibody, clone OTI2E2 (formerly 2E2), HRP conjugated | 100 ul |
$509.00
|
|
| TA502148S | MAPK7 (ERK5) mouse monoclonal antibody, clone OTI2E2 (formerly 2E2) | 30 ul |
$200.00
|
|
Citations
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