GALE Mouse Monoclonal Antibody [Clone ID: OTI1C4]

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SKU
TA502146
GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI1C4
Application IHC, Simple Western, WB
Recommended Dilution WB 1:500~2000, IHC 1:150 ; Simple Western 1:20-1:50
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GALE (NP_000394) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 38.1 kDa
Gene Name UDP-galactose-4-epimerase
Database Link
Background This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. provided by RefSeq, Jul 2008
Synonyms SDR1E1
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways
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Other "OTI1C4" antibodies (4)
SKU Description Size Price
CF502146 Carrier-free (BSA/glycerol-free) GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) 100 ug
$620.00
TA502146AM GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4), Biotinylated 100 ul
$509.00
TA502146BM GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4), HRP conjugated 100 ul
$509.00
TA502146S GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) 30 ul
$200.00

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