GALE Mouse Monoclonal Antibody [Clone ID: OTI1C4]
Specifications
| Product Data | |
| Clone Name | OTI1C4 |
|---|---|
| Application | IHC, Simple Western, WB |
| Recommended Dilution | WB 1:500~2000, IHC 1:150 ; Simple Western 1:20-1:50 |
| Reactivity | Dog, Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human GALE (NP_000394) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 38.1 kDa |
| Gene Name | UDP-galactose-4-epimerase |
| Database Link | |
| Background | This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. provided by RefSeq, Jul 2008 |
| Synonyms | SDR1E1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI1C4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF502146 | Carrier-free (BSA/glycerol-free) GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) | 100 ug |
$620.00
|
|
| TA502146AM | GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4), Biotinylated | 100 ul |
$509.00
|
|
| TA502146BM | GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4), HRP conjugated | 100 ul |
$509.00
|
|
| TA502146S | GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) | 30 ul |
$200.00
|
|
Citations
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