DHPS Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2C9]
$509.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | OTI2C9 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human DHPS (NP_001921) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA and 50% glycerol |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 40.8 kDa |
| Gene Name | deoxyhypusine synthase |
| Database Link | |
| Background | The unusual amino acid hypusine is formed posttranslationally and is only found in a single cellular protein, eukaryotic translation initiation factor 5A. In the first step of hypusine biosynthesis, deoxyhypusine synthase catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue. This gene consists of nine exons spanning 6.6 kb. Three transcript variants have been isolated. However, only transcript variant 1 encodes an active protein. The shorter variants may act as modulating factors of DHPS activity. provided by RefSeq |
| Synonyms | DHS; DS; MIG13 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI2C9" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF501393 | Carrier-free (BSA/glycerol-free) DHPS mouse monoclonal antibody, clone OTI2C9 (formerly 2C9) | 100 ug |
$620.00
|
|
| TA501393 | Anti-DHPS mouse monoclonal antibody, clone OTI2C9 (formerly 2C9) | 100 ul |
$447.00
|
|
| TA501393AM | Anti-DHPS mouse monoclonal antibody, clone OTI2C9 (formerly 2C9), Biotinylated | 100 ul |
$509.00
|
|
| TA501393S | Anti-DHPS mouse monoclonal antibody, clone OTI2C9 (formerly 2C9) | 30 ul |
$200.00
|
|
Citations
Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing
Ivanov, Shin, Loughran et al
Mol. Cell (2018) 70 (2), 254-264.e6 DOI: 10.1016/j.molcel.2018.03.015
Ivanov, Shin, Loughran et al
Mol. Cell (2018) 70 (2), 254-264.e6 DOI: 10.1016/j.molcel.2018.03.015
AI Summary: OriGene contributed to this study by providing the mouse monoclonal antibody against human DHPS, which was used for protein detection in immunoblotting experiments.
Snippet: …Cells were lysed by sonication for 5 s at output level 3 using a microtip (Fisher Scientific 550 Sonic Dismembrator), and then lysates were mixed with an equivalent volume 2X Laemmli sample buffer (Bio-Rad) and heated at 80C for 5 min. Following separation on a 4%–20% SDS-polyacrylamide gel (Bio-Rad), proteins were detected by immunoblotting with mouse monoclonal antibody against human DHPS (Origene, Rockville, MD)
Showing 1-1 of 1 papers.
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