INDOL1 (IDO2) Mouse Monoclonal Antibody [Clone ID: OTI1A4]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1A4 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:500, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human IDO2 (NP_919270) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 46.9 kDa |
| Gene Name | indoleamine 2,3-dioxygenase 2 |
| Database Link | |
| Background | Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 PubMed 17499941). supplied by OMIM |
| Synonyms | INDOL1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Metabolic pathways, Tryptophan metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI1A4" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF501378 | Carrier-free (BSA/glycerol-free) IDO2 mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) | 100 ug |
$620.00
|
|
| TA501378AM | IDO2 mouse monoclonal antibody, clone OTI1A4 (formerly 1A4), Biotinylated | 100 ul |
$509.00
|
|
| TA501378BM | IDO2 mouse monoclonal antibody, clone OTI1A4 (formerly 1A4), HRP conjugated | 100 ul |
$509.00
|
|
| TA501378S | IDO2 mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) | 30 ul |
$200.00
|
|
Citations
Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells
Jonescheit, Oberg, Gonnermann et al
Cells (2020) 9 (5) DOI: 10.3390/cells9051140
Jonescheit, Oberg, Gonnermann et al
Cells (2020) 9 (5) DOI: 10.3390/cells9051140
Cited by 40
AI Summary: OriGene products, specifically the anti-IDO-1 monoclonal antibody (clone 1A3) and anti-IDO-2 monoclonal antibody (clone 1A4), were used to detect and analyze IDO protein expression in pancreatic ductal adenocarcinoma cells by Western blotting in this study.
Snippet: In total, 106 PDAC cells were cultured in medium or treated with 100 ng/mL or 500 ng/mL rIFN-γ (R&D Systems) for 48 h. Thereafter, cells were lysed in TNE lysis buffer with 1% (v/v) Nonidet P-40 (Fluka Chemie, Buchs, Switzerland) in 50 mM Tris (Roth, Karlsruhe, Germany), 2 mM EDTA, 150 mM NaCl (Merck, Darmstadt, Karlsruhe), with phosphatase and protease inhibitors sodium fluoride and sodium orthov...
Showing 1-1 of 1 papers.
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