RANGAP1 Mouse Monoclonal Antibody [Clone ID: OTI1B4]

CAT#: TA501265

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Anti-RANGAP1 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4)



  View other "OTI1B4" antibodies (4)

Special Offer: Try sample size of this antibody at $99/€99. Use code “TrueSample”.

USD 417.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name OTI1B4
Applications FC, IF, IHC, WB
Recommended Dilution WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
Reactivities Human, Mouse, Rat, Dog
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human RANGAP1 (NP_002874) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.81 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 63.4 kDa
Gene Name Ran GTPase activating protein 1
Background RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq]
Synonyms Fug1; RANGAP; SD
Reference Data

Other Versions

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