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BIRC5 Mouse Monoclonal Antibody [Clone ID: OTI2D9]

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SKU
TA501245
Anti-BIRC5/Survivin mouse monoclonal antibody, clone OTI2D9 (formerly 2D9)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated DyLight 488 Biotin HRP
  $447.00
In Stock*
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Frequently Bought Together (3)

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View other "BIRC5 or NM_001168" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2D9
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000
IF 1:100
FLOW 1:100
IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BIRC5 (NP_001159) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 16.2 kDa
Gene Name baculoviral IAP repeat containing 5
Database Link
Background This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Synonyms API4; EPR-1
Reference Data
Protein Categories Cytokines, Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Pathways in cancer
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Other "OTI2D9" antibodies (7)
SKU Description Size Price
CF501245 Carrier-free (BSA/glycerol-free) BIRC5/Survivin mouse monoclonal antibody, clone OTI2D9 (formerly 2D9) 100 ug
$620.00
TA400023 Anti-BIRC5/Survivin mouse mAb, clone OTI2D9, DyLight488 conjugated 100 ul
$495.00
TA400024 Anti-BIRC5/Survivin mouse mAb, clone OTI2D9, Biotinylated 100 ul
$495.00
TA400025 Anti-BIRC5/Survivin mouse mAb, clone OTI2D9, HRP conjugated 100 ul
$495.00
TA501245S Anti-BIRC5/Survivin mouse monoclonal antibody, clone OTI2D9 (formerly 2D9) 30 ul
$200.00
TA600032 Purified BIRC5/Survivin mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700033 BIRC5/Survivin biotinylated mouse monoclonal detection antibody, validated for ELISA assays 50 ug
$494.00

file-alt Citations

PTK6 inhibits autophagy to promote uveal melanoma tumorigenesis by binding to SOCS3 and regulating mTOR phosphorylation
Liu, Yao, Zhang et al
Cell Death Dis (2023) 14 (1), 55 DOI: 10.1038/s41419-023-05590-w
Cited by 22
AI Summary: In this study, OriGene's PTK6 (RC217636) and SOCS3 (RC217327) overexpression plasmids were used to investigate the roles of PTK6 and SOCS3 in regulating autophagy and tumorigenesis in uveal melanoma cells.
FigureFigureFigure
Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death via Inhibiting Apoptosis
Deng, Zou, Xiong et al
J. Virol. (2017)
AI Summary: OriGene contributed to this study by providing the anti-BIRC5 antibody (#TA501245), which was used to detect BIRC5 protein expression and investigate its role in regulating cell death pathways during human bocavirus 1 (HBoV1) infection of human airway epithelial cells.
Snippet: Page 1. 1 Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death 1 via Inhibiting Apoptosis 2 3 4 Xuefeng Deng1, Wei Zou1, Min Xiong2, Zekun Wang1, John F. Engelhardt3,4, Shui Qing Ye2, 5 ...;anti-BIRC5 (#TA501245) from OriGene (Rockville, 618 MD), anti-VNN1 (#GTX114212) from GeneTex (Irvine, CA), and anti- β -actin (#A5441) from 619 Sigma
WB
Showing 1-2 of 2 papers.
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