Profilin 1 (PFN1) Mouse Monoclonal Antibody [Clone ID: OTI1D5]

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TA501211
Anti-PFN1 (Profilin 1) mouse monoclonal antibody, clone OTI1D5 (formerly 1D5)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI1D5
Application FC, IF, IHC, Simple Western, WB
Recommended Dilution WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100, Simple Western 1:20 - 1:50
Reactivity Dog, Human, Monkey
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PFN1 (NP_005013) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 14.9 kDa
Gene Name profilin 1
Database Link
Background The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.
Synonyms ALS18
Reference Data
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Regulation of actin cytoskeleton
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Other "OTI1D5" antibodies (4)
SKU Description Size Price
CF501211 Carrier-free (BSA/glycerol-free) PFN1 mouse monoclonal antibody, clone OTI1D5 (formerly 1D5) 100 ug
$620.00
TA501211AM Anti-PFN1 (Profilin 1) mouse monoclonal antibody, clone OTI1D5 (formerly 1D5), Biotinylated 100 ul
$509.00
TA501211BM Anti-PFN1 (Profilin 1) mouse monoclonal antibody, clone OTI1D5 (formerly 1D5), HRP conjugated 100 ul
$509.00
TA501211S Anti-PFN1 (Profilin 1) mouse monoclonal antibody, clone OTI1D5 (formerly 1D5) 30 ul
$200.00

file-alt Citations

Mutation analysis and immunopathological studies of PFN1 in familial and sporadic amyotrophic lateral sclerosis
Yang, Fifita, Williams et al
Neurobiol. Aging (2013) 34 (9), 2235.e7-10 DOI: 10.1016/j.neurobiolaging.2013.04.003
Cited by 22
AI Summary: OriGene’s mouse anti-PFN1 antibody was used for immunohistochemical analysis to investigate PFN1 protein pathology in ALS patient tissues in this study.
Snippet: (2012). Immunohistochemistry was performed as previously described (Williams et al., 2012). Primary antibodies were mouse anti-PFN1 (Origene, Rockville, MD, 1:500) and rabbit anti-TDP-43 (Proteintech, Chicago, IL, 1:500). 3. Results. 3.1. Genetic analysis.
IHC
Showing 1-1 of 1 papers.
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