UAP56 (DDX39B) Mouse Monoclonal Antibody [Clone ID: OTI2C5]

SKU TA501186

Anti-BAT1 (UAP56) mouse monoclonal antibody, clone OTI2C5 (formerly 2C5)

Product Data

• Clone Name: OTI2C5
• Application: IHC, WB
• Recommended Dilution: WB 1:500, IHC 1:50
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human BAT1(NP_542165) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.59 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 48.8 kDa
• Gene Name: DExD-box helicase 39B
• Database Link:
  NP_542165
  Q13838
• Background: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
• Synonyms: BAT1; D6S81E; UAP56

Reference Data

• Protein Pathways: Spliceosome