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UAP56 (DDX39B) Mouse Monoclonal Antibody [Clone ID: OTI2C5]

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SKU
TA501186
Anti-BAT1 (UAP56) mouse monoclonal antibody, clone OTI2C5 (formerly 2C5)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "UAP56 or NM_080598" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2C5
Application IHC, WB
Recommended Dilution WB 1:500, IHC 1:50
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human BAT1(NP_542165) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.59 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 48.8 kDa
Gene Name DExD-box helicase 39B
Database Link
Background This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
Synonyms BAT1; D6S81E; UAP56
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways Spliceosome
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Other "OTI2C5" antibodies (4)
SKU Description Size Price
CF501186 Carrier-free (BSA/glycerol-free) BAT1 mouse monoclonal antibody, clone OTI2C5 (formerly 2C5) 100 ug
$620.00
TA501186AM Anti-BAT1 (UAP56) mouse monoclonal antibody, clone OTI2C5 (formerly 2C5), Biotinylated 100 ul
$509.00
TA501186BM Anti-BAT1 (UAP56) mouse monoclonal antibody, clone OTI2C5 (formerly 2C5), HRP conjugated 100 ul
$509.00
TA501186S Anti-BAT1 (UAP56) mouse monoclonal antibody, clone OTI2C5 (formerly 2C5) 30 ul
$200.00

file-alt Citations

DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy
Szymura, Bernal, Wu et al
BMC Biol. (2020) 18 (1), 32 DOI: 10.1186/s12915-020-0764-z
Cited by 27
AI Summary: OriGene contributed to this study by providing the anti-DDX39B antibody (TA501186), which was used to detect DDX39B protein levels and investigate its role in regulating NF-κB activity and sensitivity to chemotherapy.
Snippet: nta Cruz, 1:10,000 dilution), anti-S-tag (688102, Biolegend, 1:10,000 dilution), anti-Sumo (PA5-11375, ThermoFisher, 1:1000 dilution), anti-DDX39B (sc-271395, Santa Cruz, 1:1000 dilution or TA501186, Origene, 1:1000 dilution), anti-PIASx (sc-166494, Santa Cruz, 1:1000 dilution), anti-Myc (sc-40, Santa Cruz, 1:10,000 dilution), anti-ubiquitin (sc-9133, Santa Cruz, 1:1000 dilution), anti-phospho-Iκ;- Nuclear factor-κB (NF-κB) plays a prominent role in promoting inflammation and resistance to DNA damaging therapy. …
FigureFigureFigure
WB IP
Showing 1-1 of 1 papers.
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