Glucose 6 phosphate isomerase (GPI) Mouse Monoclonal Antibody [Clone ID: OTI2D2]
Specifications
| Product Data | |
| Clone Name | OTI2D2 |
|---|---|
| Application | IF, IHC, Simple Western, WB |
| Recommended Dilution | WB 1:1000~2000, IHC 1:50, IF 1:100, Simple Western 1:20 - 1:50 |
| Reactivity | Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human GPI(NP_000166) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.68 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 63.0 kDa |
| Gene Name | glucose-6-phosphate isomerase |
| Database Link | |
| Background | This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. |
| Synonyms | AMF; GNPI; NLK; PGI; PHI; SA-36; SA36 |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2D2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF501171 | Carrier-free (BSA/glycerol-free) GPI mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) | 100 ug |
$620.00
|
|
| TA501171AM | Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), Biotinylated | 100 ul |
$509.00
|
|
| TA501171BM | Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), HRP conjugated | 100 ul |
$509.00
|
|
| TA501171S | Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) | 30 ul |
$200.00
|
|
Citations
Tietz, McCluskey, Miller et al
Cell Rep (2025) 44 (1), 115211 DOI: 10.1016/j.celrep.2024.115211
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