Glucose 6 phosphate isomerase (GPI) Mouse Monoclonal Antibody [Clone ID: OTI2D2]

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SKU
TA501171
Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI2D2
Application IF, IHC, Simple Western, WB
Recommended Dilution WB 1:1000~2000, IHC 1:50, IF 1:100, Simple Western 1:20 - 1:50
Reactivity Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GPI(NP_000166) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.68 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 63.0 kDa
Gene Name glucose-6-phosphate isomerase
Database Link
Background This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Synonyms AMF; GNPI; NLK; PGI; PHI; SA-36; SA36
Reference Data
Protein Categories Cardiovascular diseases, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome
Protein Pathways Amino sugar and nucleotide sugar metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway, Starch and sucrose metabolism
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Other "OTI2D2" antibodies (4)
SKU Description Size Price
CF501171 Carrier-free (BSA/glycerol-free) GPI mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) 100 ug
$620.00
TA501171AM Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), Biotinylated 100 ul
$509.00
TA501171BM Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), HRP conjugated 100 ul
$509.00
TA501171S Anti-GPI (Glucose 6 phosphate isomerase) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2) 30 ul
$200.00

file-alt Citations

CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells
Tietz, McCluskey, Miller et al
Cell Rep (2025) 44 (1), 115211 DOI: 10.1016/j.celrep.2024.115211
Cited by 5
AI Summary: In this study, the OriGene GPI antibody (RRID:AB_11129604) was used to investigate the effects of CPSF1 inhibition on polyadenylation site usage and glycolysis in prostate cancer cells.
Snippet: CPSF6 Fortis Life Sciences RRID:AB_937781 GPI Origene RRID:AB_11129604
Showing 1-1 of 1 papers.
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