Cytochrome P450 1A2 (CYP1A2) Mouse Monoclonal Antibody [Clone ID: OTI15E2]
Specifications
| Product Data | |
| Clone Name | OTI15E2 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.8 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 58.2 kDa |
| Gene Name | cytochrome P450 family 1 subfamily A member 2 |
| Database Link | |
| Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. |
| Synonyms | CP12; P3-450; P450(PA) |
| Note | WB application:Only overexpression results are guaranteed, not endogenous |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, P450, Transmembrane |
| Protein Pathways | Caffeine metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tryptophan metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI15E2" antibodies (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF501156 | Carrier-free (BSA/glycerol-free) CYP1A2 mouse monoclonal antibody, clone OTI15E2 (formerly 15E2) | 100 ug |
$620.00
|
|
| TA501156 | Anti-CYP1A2 (Cytochrome P450 1A2) mouse monoclonal antibody, clone OTI15E2 (formerly 15E2) | 100 ul |
$447.00
|
|
| TA501156AM | Anti-CYP1A2 (Cytochrome P450 1A2) mouse monoclonal antibody, clone OTI15E2 (formerly 15E2), Biotinylated | 100 ul |
$509.00
|
|
| TA501156BM | Anti-CYP1A2 (Cytochrome P450 1A2) mouse monoclonal antibody, clone OTI15E2 (formerly 15E2), HRP conjugated | 100 ul |
$509.00
|
|
| TA700038 | CYP1A2 biotinylated mouse monoclonal detection antibody, validated for ELISA assays | 50 ug |
$494.00
|
|
Citations
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