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MAPK11 Mouse Monoclonal Antibody [Clone ID: OTI1C2]

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SKU
TA501085
Anti-MAPK11 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
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View other "MAPK11 or NM_002751" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1C2
Application IF, WB
Recommended Dilution WB 1:2000, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MAPK11 (NP_002742) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 41.4 kDa
Gene Name mitogen-activated protein kinase 11
Database Link
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
Synonyms p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
Reference Data
Protein Categories Cytokines, Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway
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Other "OTI1C2" antibodies (4)
SKU Description Size Price
CF501085 Carrier-free (BSA/glycerol-free) MAPK11 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2) 100 ug
$620.00
TA501085AM Anti-MAPK11 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2), Biotinylated 100 ul
$509.00
TA501085BM Anti-MAPK11 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2), HRP conjugated 100 ul
$509.00
TA501085S Anti-MAPK11 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2) 30 ul
$200.00

file-alt Citations

Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor
Bhattacharjee, Bakar, Chitnis et al
Cell Chem Biol (2023) 30 (10), 1211-1222.e5 DOI: 10.1016/j.chembiol.2023.09.013
Cited by 27
AI Summary: OriGene's Mouse monoclonal anti-MAPK11 antibody (Cat# TA501085AM) was used in this study to detect MAPK11 protein levels, contributing to the investigation of ralimetinib’s mechanism of action in cancer cells.
Snippet: Mouse monoclonal anti-MAPK11 Origene Technologies Cat# TA501085AM Mouse monoclonal anti-GAPDH-HRP Santa Cruz Biotechnology Cat# sc-365062 RRID: AB_10847862
Showing 1-1 of 1 papers.
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