TPMT Mouse Monoclonal Antibody [Clone ID: OTI2A2]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2A2 |
|---|---|
| Application | IF, IHC, WB |
| Recommended Dilution | WB 1:1000, IHC 1:50, IF 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.73 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 28.2 kDa |
| Gene Name | thiopurine S-methyltransferase |
| Database Link | |
| Background | This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. |
| Synonyms | OTTHUMP00000016076; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; thiopurine S-methyltransferase |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - other enzymes |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2A2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF500966 | Carrier-free (BSA/glycerol-free) TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2) | 100 ug |
$620.00
|
|
| TA500966AM | Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2), Biotinylated | 100 ul |
$509.00
|
|
| TA500966BM | Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2), HRP conjugated | 100 ul |
$509.00
|
|
| TA500966S | Anti-TPMT mouse monoclonal antibody, clone OTI2A2 (formerly 2A2) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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