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HSP90AA1 Mouse Monoclonal Antibody [Clone ID: OTI3B5]

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SKU
TA500883
Anti-HSP90AA1 (Hsp90 alpha) mouse monoclonal antibody, clone OTI3B5 (formerly 3B5)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "HSP90AA1 or NM_005348" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3B5
Application WB
Recommended Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human HSP90AA1 (NP_005339) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 84.7 kDa
Gene Name heat shock protein 90 alpha family class A member 1
Database Link
Background HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding,protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria
Synonyms EL52; HSP86; Hsp89; HSP89A; Hsp90; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; LAP-2; LAP2
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer
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Other "OTI3B5" antibodies (4)
SKU Description Size Price
CF500883 Carrier-free (BSA/glycerol-free) HSP90AA1 mouse monoclonal antibody, clone OTI3B5 (formerly 3B5) 100 ug
$620.00
TA500883AM Anti-HSP90AA1 (Hsp90 alpha) mouse monoclonal antibody, clone OTI3B5 (formerly 3B5), Biotinylated 100 ul
$509.00
TA500883BM Anti-HSP90AA1 (Hsp90 alpha) mouse monoclonal antibody, clone OTI3B5 (formerly 3B5), HRP conjugated 100 ul
$509.00
TA500883S Anti-HSP90AA1 (Hsp90 alpha) mouse monoclonal antibody, clone OTI3B5 (formerly 3B5) 30 ul
$200.00

file-alt Citations

PPARγΔ5, a Naturally Occurring Dominant-Negative Splice Isoform, Impairs PPARγ Function and Adipocyte Differentiation
Aprile, Cataldi, Ambrosio et al
Cell Rep (2018) 25 (6), 1577-1592.e6 DOI: 10.1016/j.celrep.2018.10.035
AI Summary: OriGene’s SRSF1 Trilencer-27 Human siRNAs (SR304331) were used in this study to selectively knock down SRSF1 expression, enabling the authors to investigate its role in the alternative splicing and regulation of the novel PPARγΔ5 isoform.
Snippet: Coding regions of canonical PPARG, PPARGΔ5, and SRSF1 were cloned into pcDNA3.1/V5-His-TOPO (Life Technologies, Carlsbad, CA, USA) in-frame with the V5 and His epitopes. … Three different SRSF1 Trilencer-27 Human siRNA (SR304331, OriGene, Rockville, USA) were tested and the A+C combination of siRNAs was selected for the further analyses
Helicobacter pylori Affects the Antigen Presentation Activity of Macrophages Modulating the Expression of the Immune Receptor CD300E through miR-4270
Pagliari, Munari, Toffoletto et al
Front Immunol (2017) 8, 1288 DOI: 10.3389/fimmu.2017.01288
AI Summary: In this study, the OriGene monoclonal anti-HSP90 antibody was used to detect HSP90 protein levels in macrophages, aiding in the analysis of how Helicobacter pylori infection modulates immune receptor expression and antigen presentation.
Snippet: Helicobacter pylori (Hp) is a Gram-negative bacterium that infects the human gastric mucosa, leading to chronic inflammation. If not eradicated with antibiotic treatment, the bacterium persists in the human stomach for decades increasing the risk to develop chronic gastritis ... Cached;Membranes were blocked with 5% non-fat milk in Tris-buffered saline (TBS, 50 mM Tris–HCl pH 7.6, ...
FigureFigureFigure
WB
Showing 1-2 of 2 papers.
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