GBP2 Mouse Monoclonal Antibody [Clone ID: OTI1E5]

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SKU
TA500657
GBP2 mouse monoclonal antibody, clone OTI1E5 (formerly 1E5)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI1E5
Application FC, IF, IHC
Recommended Dilution IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Dog, Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GBP2 (NP_004111) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1.26 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 67 kDa
Gene Name guanylate binding protein 2
Database Link
Background Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP. provided by RefSeq
Synonyms DKFZp451C2311
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI1E5" antibodies (4)
SKU Description Size Price
CF500657 Carrier-free (BSA/glycerol-free) GBP2 mouse monoclonal antibody, clone OTI1E5 (formerly 1E5) 100 ug
$620.00
TA500657AM GBP2 mouse monoclonal antibody, clone OTI1E5 (formerly 1E5), Biotinylated 100 ul
$509.00
TA500657BM GBP2 mouse monoclonal antibody, clone OTI1E5 (formerly 1E5), HRP conjugated 100 ul
$509.00
TA500657S GBP2 mouse monoclonal antibody, clone OTI1E5 (formerly 1E5) 30 ul
$200.00

file-alt Citations

HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression
Srinivasachar Badarinarayan, Shcherbakova, Langer et al
Nucleic Acids Res (2020)
Cited by 99
AI Summary: OriGene's anti-GBP2 antibody (TA500657) was used to stain cells and detect GBP2 protein expression, helping to assess the regulation of antiviral gene expression in the study.
Snippet: Subsequently, cells were stained using anti-GBP1 (Santa Cruz, #sc-53857), anti- GBP2 (Origene, #TA500657), anti-GBP5 (Santa Cruz, #sc- 160353) and the following secondary antibodies: goat anti- rat, APC-conjugated (life technologies, #A10540), goat anti-mouse
FC
Identification of interferon-stimulated genes that attenuate Ebola virus infection
Kuroda, Halfmann, Hill-Batorski et al
Nat Commun (2020) 11 (1), 2953 DOI: 10.1038/s41467-020-16768-7
Cited by 56
AI Summary: In this study, OriGene products ODC1 (TA501546) and GBP2 (TA500657) antibodies were used to detect the expression of specific interferon-stimulated genes during experiments assessing their ability to attenuate Ebola virus infection.
Snippet: EBOV VP30 (1:1000, cl. 3), EBOV VP24 (1:1000, cl. 21-5.2.5), alpha-tubulin (1:1000, ab7291, Abcam), PFKFB3 (1:1000, 13132, Cell signaling technology), ODC1 (1:1000, TA501546, Origene), MAP3K5 (1:1000, 8662, Cell signaling technology), AKT3 (1:1000, 3788, Cell signaling technology), GBP2 (1:1000, TA500657, Origene),
FigureFigureFigure
WB
Showing 1-2 of 2 papers.
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