BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: OTI6E5]
Specifications
| Product Data | |
| Clone Name | OTI6E5 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB: 1:200 - 1:1000, IHC 1:50, IF 1:100, Flow 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full-length protein expressed in 293T cell transfected with human BUB1B expression vector |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 119.5 kDa |
| Gene Name | BUB1 mitotic checkpoint serine/threonine kinase B |
| Database Link | |
| Background | This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. |
| Synonyms | Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1 |
| Reference Data | |
| Protein Categories | Cancer: Gastrointestinal, Enzyme: Kinases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
| Protein Pathways | Cell cycle |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI6E5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF500607 | Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone OTI6E5 (formerly 6E5) | 100 ug |
$620.00
|
|
| TA500607AM | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI6E5 (formerly 6E5), Biotinylated | 100 ul |
$509.00
|
|
| TA500607BM | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI6E5 (formerly 6E5), HRP conjugated | 100 ul |
$509.00
|
|
| TA500607S | Anti-BUB1B (BubR1) mouse monoclonal antibody, clone OTI6E5 (formerly 6E5) | 30 ul |
$200.00
|
|
Citations
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