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PSENEN Rabbit Monoclonal Antibody

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SKU
TA426771
PSENEN Rabbit Monoclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $435.00
3 Weeks*
Bulk/Customize

View other "PSENEN" antibodies

Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution WB:1/1000-6000
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Monoclonal
Buffer PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 12kDa
Database Link
Background Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants.
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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