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COMT Rabbit Monoclonal Antibody

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SKU
TA426286
COMT Rabbit Monoclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $435.00
3 Weeks*
Bulk/Customize

View other "COMT" antibodies

Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution WB,1:500 - 1:1000
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Monoclonal
Buffer PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 30kDa
Database Link
Background Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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