Phospho STAT1 (Tyr701) Rabbit Monoclonal Antibody [Clone ID: OTIRA0616]
Specifications
| Product Data | |
| Clone Name | OTIRA0616 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:1000~1:2000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthesized peptide derived from human STAT1 |
| Specificity | Phospho-STAT1 (Y701) Antibody detects endogenous levels of Phospho-STAT1 (Y701) |
| Buffer | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
| Storage | Store at +4°C short term. Store at -22°C long term. Avoid freeze / thaw cycle. |
| Shipping | Blue Ice |
| Predicted Protein Size | 87kDa |
| Gene Name | signal transducer and activator of transcription 1 |
| Database Link | |
| Background | The Stat1 transcription factor is activated in response to a large number of ligands and is essential for responsiveness to IFN-α and IFN-γ. Stat1 protein exists as a pair of isoforms, Stat1α (91 kDa) and the splice variant Stat1β (84 kDa). In most cells, both isoforms are activated by IFN-α, but only Stat1α is activated by IFN-γ. The inappropriate activation of Stat1 occurs in many tumors. |
| Synonyms | CANDF7; ISGF 3; Signal transducer and activator of transcription 1; Stat1; STAT91; Transcription factor ISGF-3 components p91/p84 |
| Reference Data | |
| Protein Categories | Chemokines, Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Transciption Factors |
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