Dxd Rabbit Monoclonal Antibody [Clone ID: 1E6]
$255.00
2 Weeks*
Specifications
| Product Data | |
| Clone Name | 1E6 |
|---|---|
| Application | ELISA |
| Recommended Dilution | ELISA 1:5000-10000 |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Reconstitution Method | Reconstitute with sterile, low-endotoxin water. See the COA for more details |
| Concentration | Lot specific |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Database Link | |
| Background | Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3. |
| Synonyms | N.A. |
| Reference Data | |
Reviews
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| Product Manuals |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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