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Dxd Rabbit Monoclonal Antibody [Clone ID: 1A5]

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SKU
TA421201
Anti-Dxd antibody(1A5); Rabbit mAb
Size:
100 ug 10 ug
Conjugation:
Unconjugated Biotin
  $750.00
2 Weeks*
Bulk/Customize

View other "Dxd" antibodies

Specifications
Specifications
Product Data
Clone Name 1A5
Application ELISA
Recommended Dilution ELISA 1:5000-10000
Antibody Host Rabbit
Isotype IgG
Clonality Monoclonal
Buffer 50% Glycerol; PBS, pH 7.4; 0.1% BSA Preservative: 0.1% Procline 300
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Purification Purified from cell culture supernatant by affinity chromatography
Conjugation Unconjugated
Storage Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing)
Stability 12 months from date of despatch
Shipping Ambient
Database Link
Background Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3.
Synonyms N.A.
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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